Summary: | Background. Febrile seizure is the most common form of seizure in children
between 6 months to 5 years of age. It occur in 2-5 % children and has good
prognosis. Zinc has an important role in development of the central nervous
system. The study about serum zinc level in children with febrile seizure was
limited.
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Objective. To compare the serum zinc level in children with and without febrile
seizure and correlation between serum zinc level and febril seizure.
Methods. A case-control study was conducted during July 2012 to October 2012
in Dr. Sardjito General Hospital and Sleman General Hospital, Yogyakarta.
Thirty-eight children aged 6 months to 5 years with febrile seizure and 38 children
with febrile without seizure were entrolled. Serum zinc level was measured using
atomic absorption spectrophotometry. Data was analized with independent t test,
chi-suare n spearman.
Results. The mean serum zinc level in children with febrile seizure and children
with febrile without seizure were 95.4 ug/dL and 100.9 ug/dL, respectively. There
was no significant difference statistically between serum zinc level and febrile
seizure in children [OR 1,49 (CI 95 % 0,428 to 5,191), P= 0,529].
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