PENGARUH KONSENTRASI KARBONAT APATIT TERHADAP PROFIL DEGRADASI FREEZE DRIED HIDROGEL-CHA

Surgical Procedures for bone rehabilitation have been being continously developed due to high incidence of bone damage. Bone damage repair process can be done using scaffold to promote osseoninduction, osseconduction and osseointegration. Ideal scaffold have porous and biodegradable. Hydrogel-CHA wa...

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Bibliographic Details
Main Authors: , MUHAMMAD FUADI, , drg. Ika Dewi Ana, M.Kes., Ph.D
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2013
Subjects:
ETD
Description
Summary:Surgical Procedures for bone rehabilitation have been being continously developed due to high incidence of bone damage. Bone damage repair process can be done using scaffold to promote osseoninduction, osseconduction and osseointegration. Ideal scaffold have porous and biodegradable. Hydrogel-CHA was novel bone scaffolds that widely developed in bone remodelling technology. the aim of this study was to determine the effect of CHA on freeze dried hydrogel-CHA degradation profile. Hydrogel-CHA was prepared by synthetizing CHA in gelatin solution continued by freeze drying and were crosslinked with dehydhothermal (DHT) process. the subjects of this research were 10 mg freeze-dried hydrogel-CHA with various gelatin-CHA composition, ranged from 10/00