| Summary: | The ethanolic extract of Homalanthus populneus contains a unique phorbolester
called prostratin. Prostratin has an anti-viral activity and cytoprotective effect
on monocyte, macrophage, and T cells infected by HIV-1. This study aims to
determine the activity of ethanolic extract of Homalanthus populneus (Geisel.) Pax�s
stems on human peripheral blood mononuclear cell (PBMC) and mice macrophages.
The cytotoxicity effect of ethanolic extract of H. populneus was assessed using the MTT
assay. There were a control group, solvent control (DMSO 0.125 % and 0.25 %),
positive control (Lipopolysaccharides (LPS) 1, 10, 50 mg/mL for macrophages), and
an extract treatment group (7.8125
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