EFEK ANTI-INFLAMASI EKSTRAK AQUOSA SARANG BURUNG WALET MELALUI PENGHAMBATAN EKSPRESI mRNA SIKLOOKSIGENASE (COX-2) PADA MENCIT (Mus musculus L.) YANG DIINDUKSI KARAGENAN
  Edible bird�s nest is well known as a tradisional medicinal food in China. This reseach to investigated the anti-inflamatory effect of aqueous of edible bird�s nest to inhibition the expresion of mRNA siklooksigenase (COX-2) on mice (Mus musculus L). Carragenan induced paw edema was use in...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2013
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| _version_ | 1797034357063417856 |
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| author | , NURJANAH , Nastiti Dr.biol.hom. Wijayanti, S.Si., M.Si. |
| author_facet | , NURJANAH , Nastiti Dr.biol.hom. Wijayanti, S.Si., M.Si. |
| author_sort | , NURJANAH |
| collection | UGM |
| description |   Edible bird�s nest is well known as a tradisional medicinal food in China. This
reseach to investigated the anti-inflamatory effect of aqueous of edible bird�s nest to
inhibition the expresion of mRNA siklooksigenase (COX-2) on mice (Mus musculus L).
Carragenan induced paw edema was use in this reseach. Injection of caragenan into the
food if a mice elicited in acute inflamatory response. Natrium diklofenak dose 10,28mg/ml
was use as a positive control and the mice were orally administrated with Aqueous extract
of edible bird�s nest 1 hour before carragenan injection. Different dose of aqueous extract
of ediblr bird�s nest were used respectively 0,135 mg/gram BB, P2 dosis 1,38 mg/gram
BB, dan P3 dengan dosis 14,1 mg/gram BB .Total RNA was isolated from peritoneal
macrophages after 4 hour of carragenan treatment. While COX-2 expression was
determined by RT-PCR using specific primer. Electroforesis is used to detection mRNA
COX-2 Expression and read with UV- transluminator. This result showed that aqueous
extract of edible bird�s nest doses 0,135-14,1mg/gram BB can inhibited COX-2 expression. |
| first_indexed | 2024-03-13T23:10:21Z |
| format | Thesis |
| id | oai:generic.eprints.org:125368 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T23:10:21Z |
| publishDate | 2013 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1253682016-03-04T08:41:19Z https://repository.ugm.ac.id/125368/ EFEK ANTI-INFLAMASI EKSTRAK AQUOSA SARANG BURUNG WALET MELALUI PENGHAMBATAN EKSPRESI mRNA SIKLOOKSIGENASE (COX-2) PADA MENCIT (Mus musculus L.) YANG DIINDUKSI KARAGENAN , NURJANAH , Nastiti Dr.biol.hom. Wijayanti, S.Si., M.Si. ETD   Edible bird�s nest is well known as a tradisional medicinal food in China. This reseach to investigated the anti-inflamatory effect of aqueous of edible bird�s nest to inhibition the expresion of mRNA siklooksigenase (COX-2) on mice (Mus musculus L). Carragenan induced paw edema was use in this reseach. Injection of caragenan into the food if a mice elicited in acute inflamatory response. Natrium diklofenak dose 10,28mg/ml was use as a positive control and the mice were orally administrated with Aqueous extract of edible bird�s nest 1 hour before carragenan injection. Different dose of aqueous extract of ediblr bird�s nest were used respectively 0,135 mg/gram BB, P2 dosis 1,38 mg/gram BB, dan P3 dengan dosis 14,1 mg/gram BB .Total RNA was isolated from peritoneal macrophages after 4 hour of carragenan treatment. While COX-2 expression was determined by RT-PCR using specific primer. Electroforesis is used to detection mRNA COX-2 Expression and read with UV- transluminator. This result showed that aqueous extract of edible bird�s nest doses 0,135-14,1mg/gram BB can inhibited COX-2 expression. [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , NURJANAH and , Nastiti Dr.biol.hom. Wijayanti, S.Si., M.Si. (2013) EFEK ANTI-INFLAMASI EKSTRAK AQUOSA SARANG BURUNG WALET MELALUI PENGHAMBATAN EKSPRESI mRNA SIKLOOKSIGENASE (COX-2) PADA MENCIT (Mus musculus L.) YANG DIINDUKSI KARAGENAN. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=65535 |
| spellingShingle | ETD , NURJANAH , Nastiti Dr.biol.hom. Wijayanti, S.Si., M.Si. EFEK ANTI-INFLAMASI EKSTRAK AQUOSA SARANG BURUNG WALET MELALUI PENGHAMBATAN EKSPRESI mRNA SIKLOOKSIGENASE (COX-2) PADA MENCIT (Mus musculus L.) YANG DIINDUKSI KARAGENAN |
| title | EFEK ANTI-INFLAMASI EKSTRAK AQUOSA SARANG BURUNG WALET
MELALUI PENGHAMBATAN EKSPRESI mRNA SIKLOOKSIGENASE (COX-2) PADA
MENCIT (Mus musculus L.) YANG DIINDUKSI KARAGENAN |
| title_full | EFEK ANTI-INFLAMASI EKSTRAK AQUOSA SARANG BURUNG WALET
MELALUI PENGHAMBATAN EKSPRESI mRNA SIKLOOKSIGENASE (COX-2) PADA
MENCIT (Mus musculus L.) YANG DIINDUKSI KARAGENAN |
| title_fullStr | EFEK ANTI-INFLAMASI EKSTRAK AQUOSA SARANG BURUNG WALET
MELALUI PENGHAMBATAN EKSPRESI mRNA SIKLOOKSIGENASE (COX-2) PADA
MENCIT (Mus musculus L.) YANG DIINDUKSI KARAGENAN |
| title_full_unstemmed | EFEK ANTI-INFLAMASI EKSTRAK AQUOSA SARANG BURUNG WALET
MELALUI PENGHAMBATAN EKSPRESI mRNA SIKLOOKSIGENASE (COX-2) PADA
MENCIT (Mus musculus L.) YANG DIINDUKSI KARAGENAN |
| title_short | EFEK ANTI-INFLAMASI EKSTRAK AQUOSA SARANG BURUNG WALET
MELALUI PENGHAMBATAN EKSPRESI mRNA SIKLOOKSIGENASE (COX-2) PADA
MENCIT (Mus musculus L.) YANG DIINDUKSI KARAGENAN |
| title_sort | efek anti inflamasi ekstrak aquosa sarang burung walet melalui penghambatan ekspresi mrna siklooksigenase cox 2 pada mencit mus musculus l yang diinduksi karagenan |
| topic | ETD |
| work_keys_str_mv | AT nurjanah efekantiinflamasiekstrakaquosasarangburungwaletmelaluipenghambatanekspresimrnasiklooksigenasecox2padamencitmusmusculuslyangdiinduksikaragenan AT nastitidrbiolhomwijayantissimsi efekantiinflamasiekstrakaquosasarangburungwaletmelaluipenghambatanekspresimrnasiklooksigenasecox2padamencitmusmusculuslyangdiinduksikaragenan |