| Summary: | Background: Incomplete abortion has contributed to maternal morbidity and
mortality. Misoprostol can be used as an alternative management of incomplete
abortion beside surgical procedure. Curettage is a surgical management that
became standard procedure in incomplete abortion at Sardjito hospital. Studies
showed that a single dose 600 μg oral misoprostol has a highly success rate in
the management of incomplete abortion.
Objective: Comparing the success rate of a single dose 600 μg oral misoprostol
to curettage in the management of incomplete abortion which gestational age
less than 12 weeks.
Design of study: Randomized controlled trial
Material and method: The eligible subjects of this study were randomized to
misoprostol management or to curettage management. The primary outcome
was success rate of the intervention, while the secondary outcome was the
incidence of infection and bleeding. Follow-up of patients was performed 1 week
after the intervention. Patients, who failed to achieve success of treatment, were
offered to get curettage.
Results: The success of treatment was achieved in 48 patients (84,2%) of
misoprostol group and 54 patients (100%) of curettage group. The relative risk
success rate of misoprostol was 0,84 (95%CI 0,75-0,94). The incidence of
infection was not found in both treatment groups. Incidence of bleeding was 1
patient (1.8%) of misoprostol group, whereas in the curettage group not found the
incidence of bleeding after the intervention.
Conclusion: Single dose of oral misoprostol 600 μg has success rate lower than
curettage in the management of incomplete abortion less than 12 weeks of
gestational age, the difference was statistically significant. Curettage procedure is
the first choice for management of incomplete abortion.
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