| Summary: | Laringospasm and cough are complications of extubation in pediatrics
under light anesthesia. Incidence of laringospasme in patients aged zero to nine
years is 17, 9 %. Laryngospasm is a frequently encountered complication in
children undergoing upper airway surgery, which, if left untreated, can lead to an
increase in morbidity and mortality. During emergence from general anesthesia,
airway irritation at extubation causes coughing which often causes serious
sideeffects, but coughing is accepted as a biological response that protects the
airway from aspiration.
The purpose of this study is to compare the effect of lidocaine 1,5 mg kg-1
and propofol 0,25 mg kg-1 to reduce laringospasm and cough during extubation
in pediatrics.
This study was designed on a double blind randomaized controlled trial.
One hundred and sixthy four children aged between 1 and 12 years, American
Society of Anesthesiologists (ASA) status I-II, who were undergoing elective
surgery under general anesthesia were enrolled in this randomized double blind
study. Subjects devided into two groups : lidocain group (L group) and propofol
group (P group). L group received lidocaine 1,5 mg kg-1 intravenous before
extubation, and P group received propofol 0,25 mg kg-1 intravenous before
extubation. The signs of laringospasm and cough were evaluated and recorded
until 5 minutes after extubation.
The results of the study were the incidency of laryngospasm in propofol
group less than lidocain group (4,9 %, vs 7,3 %), but statistically were not
significant (p > 0,05) and the incidency of cough in propofol group more high
than lidocain group (23,2% vs 15,9 %), statistically were not significant.
Conclusion : Administration of 0,25 mg/kg of propofol i.v has similar
efficacy to avoid laringospasm and cough during extubation when compared with
administration of 1.5 mg/kg i.v of lidocaine
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