PERBANDINGAN EFEK PROFILAKSIS MUAL DAN MUNTAH PASCAOPERASI DEKSAMETASON 10 MG INTRAVENA DAN ONDANSETRON 4 MG INTRAVENA PADA OPERASI TUBEKTOMI DENGAN ANESTESIA INTRAVENA TOTAL
Background. Tubectomy is a gynecologic procedure that is often used. Total intravenous anesthesia (TIVA) can be provided using a combination of opioid and benzodiazepine. Postoperative nausea and vomiting (PONV) is one of the common complains following this anesthesia procedure and can results in de...
| Main Authors: | , |
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| Format: | Thesis |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2013
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| Subjects: |
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| author | , SAID SHOFWAN , dr. Pandit Sarosa, Sp.An., (K). |
| author_facet | , SAID SHOFWAN , dr. Pandit Sarosa, Sp.An., (K). |
| author_sort | , SAID SHOFWAN |
| collection | UGM |
| description | Background. Tubectomy is a gynecologic procedure that is often used. Total intravenous
anesthesia (TIVA) can be provided using a combination of opioid and benzodiazepine.
Postoperative nausea and vomiting (PONV) is one of the common complains following
this anesthesia procedure and can results in decrease of patient�s satisfaction and delay in
hospital discharge, especially since this is a one day surgery. Dexamethasone and
ondansetron can be used as prophylactic antiemetic drugs.
Objective.To compare the antiemetic prophylactic effect of 10 mg intravenous
dexamethasone and of 4 mg intravenous ondansetron in tubectomy with total intravenous
anesthesia (TIVA) using intravenous meperidine 2 mg/kg BW and diazepam 0,2 mg/kg
BW.
Methods. A prospective, randomized double blind controlled trial study was performed
in 96 patients with physical status according to ASA classification class I and II
underwent general anesthesia with TIVA using meperidine 2 mg/kg BW. Patients was
randomly allocated into two groups, in which group 1 was receiveddexamethasone 10 mg
intravenously and group 2wasreceivedondansetron 4 mg intravenously. The scores of
nausea and vomituswas calculated and analyzed statistically using Chi-square test. P
value of < 0,05 means statistically different.
Results.The incidence of PONV in 10 mg intravenous dexamethason group and 4 mg
intravenous ondansetron group had no significance different (p>0,05). Statistically, both
groups had same advantages and disadvantages to diminished incidence of PONV. 10 mg
10 mg intravenous dexamethasone group had lesser patients suffered from PONV (7 of
48 patients) than 4 mg intravenous ondansetron group (10 of 48 patients). All of the
patients in dexamethason group suffered PONVrepeatedly but only 6 of 10 patients in
ondansetron group experienced it and the remaining just once.
Conclusion.10 mg intravenousdexamethasone prophylactic was as same effective as 4
mg intravenous ondansetron prophylactic for prevention of PONV in tubectomy used
TIVA with meperidine 2 mg/kgBW and diazepam 0,2 mg/kgBW. |
| first_indexed | 2024-03-13T23:12:30Z |
| format | Thesis |
| id | oai:generic.eprints.org:126025 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T23:12:30Z |
| publishDate | 2013 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1260252016-03-04T08:43:01Z https://repository.ugm.ac.id/126025/ PERBANDINGAN EFEK PROFILAKSIS MUAL DAN MUNTAH PASCAOPERASI DEKSAMETASON 10 MG INTRAVENA DAN ONDANSETRON 4 MG INTRAVENA PADA OPERASI TUBEKTOMI DENGAN ANESTESIA INTRAVENA TOTAL , SAID SHOFWAN , dr. Pandit Sarosa, Sp.An., (K). ETD Background. Tubectomy is a gynecologic procedure that is often used. Total intravenous anesthesia (TIVA) can be provided using a combination of opioid and benzodiazepine. Postoperative nausea and vomiting (PONV) is one of the common complains following this anesthesia procedure and can results in decrease of patient�s satisfaction and delay in hospital discharge, especially since this is a one day surgery. Dexamethasone and ondansetron can be used as prophylactic antiemetic drugs. Objective.To compare the antiemetic prophylactic effect of 10 mg intravenous dexamethasone and of 4 mg intravenous ondansetron in tubectomy with total intravenous anesthesia (TIVA) using intravenous meperidine 2 mg/kg BW and diazepam 0,2 mg/kg BW. Methods. A prospective, randomized double blind controlled trial study was performed in 96 patients with physical status according to ASA classification class I and II underwent general anesthesia with TIVA using meperidine 2 mg/kg BW. Patients was randomly allocated into two groups, in which group 1 was receiveddexamethasone 10 mg intravenously and group 2wasreceivedondansetron 4 mg intravenously. The scores of nausea and vomituswas calculated and analyzed statistically using Chi-square test. P value of < 0,05 means statistically different. Results.The incidence of PONV in 10 mg intravenous dexamethason group and 4 mg intravenous ondansetron group had no significance different (p>0,05). Statistically, both groups had same advantages and disadvantages to diminished incidence of PONV. 10 mg 10 mg intravenous dexamethasone group had lesser patients suffered from PONV (7 of 48 patients) than 4 mg intravenous ondansetron group (10 of 48 patients). All of the patients in dexamethason group suffered PONVrepeatedly but only 6 of 10 patients in ondansetron group experienced it and the remaining just once. Conclusion.10 mg intravenousdexamethasone prophylactic was as same effective as 4 mg intravenous ondansetron prophylactic for prevention of PONV in tubectomy used TIVA with meperidine 2 mg/kgBW and diazepam 0,2 mg/kgBW. [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , SAID SHOFWAN and , dr. Pandit Sarosa, Sp.An., (K). (2013) PERBANDINGAN EFEK PROFILAKSIS MUAL DAN MUNTAH PASCAOPERASI DEKSAMETASON 10 MG INTRAVENA DAN ONDANSETRON 4 MG INTRAVENA PADA OPERASI TUBEKTOMI DENGAN ANESTESIA INTRAVENA TOTAL. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=66213 |
| spellingShingle | ETD , SAID SHOFWAN , dr. Pandit Sarosa, Sp.An., (K). PERBANDINGAN EFEK PROFILAKSIS MUAL DAN MUNTAH PASCAOPERASI DEKSAMETASON 10 MG INTRAVENA DAN ONDANSETRON 4 MG INTRAVENA PADA OPERASI TUBEKTOMI DENGAN ANESTESIA INTRAVENA TOTAL |
| title | PERBANDINGAN EFEK PROFILAKSIS MUAL DAN MUNTAH PASCAOPERASI DEKSAMETASON 10 MG INTRAVENA DAN ONDANSETRON 4 MG INTRAVENA PADA OPERASI
TUBEKTOMI DENGAN ANESTESIA
INTRAVENA TOTAL |
| title_full | PERBANDINGAN EFEK PROFILAKSIS MUAL DAN MUNTAH PASCAOPERASI DEKSAMETASON 10 MG INTRAVENA DAN ONDANSETRON 4 MG INTRAVENA PADA OPERASI
TUBEKTOMI DENGAN ANESTESIA
INTRAVENA TOTAL |
| title_fullStr | PERBANDINGAN EFEK PROFILAKSIS MUAL DAN MUNTAH PASCAOPERASI DEKSAMETASON 10 MG INTRAVENA DAN ONDANSETRON 4 MG INTRAVENA PADA OPERASI
TUBEKTOMI DENGAN ANESTESIA
INTRAVENA TOTAL |
| title_full_unstemmed | PERBANDINGAN EFEK PROFILAKSIS MUAL DAN MUNTAH PASCAOPERASI DEKSAMETASON 10 MG INTRAVENA DAN ONDANSETRON 4 MG INTRAVENA PADA OPERASI
TUBEKTOMI DENGAN ANESTESIA
INTRAVENA TOTAL |
| title_short | PERBANDINGAN EFEK PROFILAKSIS MUAL DAN MUNTAH PASCAOPERASI DEKSAMETASON 10 MG INTRAVENA DAN ONDANSETRON 4 MG INTRAVENA PADA OPERASI
TUBEKTOMI DENGAN ANESTESIA
INTRAVENA TOTAL |
| title_sort | perbandingan efek profilaksis mual dan muntah pascaoperasi deksametason 10 mg intravena dan ondansetron 4 mg intravena pada operasi tubektomi dengan anestesia intravena total |
| topic | ETD |
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