| Summary: | Dengue infection is one of the main causes of morbidity and mortality of
children in Indonesia. Since it is known that earlier treatment and supportive therapies
can decreased case fatality rate from DHF, identification of the person who has risk to
develop to DHF must be quickly found mainly in areas of endemic. The purpose of
these studies is to find a correlation between increase of quantitative sNS with clinical
history of severe dengue infection, and also to determine the cutt off point of
quantitative sNS1 with the probability severe dengue infection. This research is a
cross-sectional study conducted on children with dengue infection in Tropical
Infections Division of The children's Health Department, Denpasar. Detection of the
antigen is made by examining sNS1 immuno-assay. Analysis correlation of Spearman
test used to look the relationship between increased quantitative sNS1 with clinical
history of severe dengue. ROC curve and the AUC used to determine the cutt off
point of quantitative sNS1 with the probability severe dengue infection. This research
found a strong positive relationship between sNS1and clinical history of severe
dengue with a value of r = 0.903, p<0.001. Spearman analysis showed that increased
sNS1 have positive correlation with severe dengue infection.
|
|---|