KORELASI ANTIGEN NS1 KUANTITATIF TERHADAP DERAJAT KEPARAHAN INFEKSI DENGUE

Dengue infection is one of the main causes of morbidity and mortality of children in Indonesia. Since it is known that earlier treatment and supportive therapies can decreased case fatality rate from DHF, identification of the person who has risk to develop to DHF must be quickly found mainly in are...

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Main Authors: , Ni Made Adi Purnami, , Prof. dr. Mohammad Juffrie, Ph.D, Sp.A(K)
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2013
Subjects:
ETD
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author , Ni Made Adi Purnami
, Prof. dr. Mohammad Juffrie, Ph.D, Sp.A(K)
author_facet , Ni Made Adi Purnami
, Prof. dr. Mohammad Juffrie, Ph.D, Sp.A(K)
author_sort , Ni Made Adi Purnami
collection UGM
description Dengue infection is one of the main causes of morbidity and mortality of children in Indonesia. Since it is known that earlier treatment and supportive therapies can decreased case fatality rate from DHF, identification of the person who has risk to develop to DHF must be quickly found mainly in areas of endemic. The purpose of these studies is to find a correlation between increase of quantitative sNS with clinical history of severe dengue infection, and also to determine the cutt off point of quantitative sNS1 with the probability severe dengue infection. This research is a cross-sectional study conducted on children with dengue infection in Tropical Infections Division of The children's Health Department, Denpasar. Detection of the antigen is made by examining sNS1 immuno-assay. Analysis correlation of Spearman test used to look the relationship between increased quantitative sNS1 with clinical history of severe dengue. ROC curve and the AUC used to determine the cutt off point of quantitative sNS1 with the probability severe dengue infection. This research found a strong positive relationship between sNS1and clinical history of severe dengue with a value of r = 0.903, p<0.001. Spearman analysis showed that increased sNS1 have positive correlation with severe dengue infection.
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spelling oai:generic.eprints.org:1260902016-03-04T08:41:25Z https://repository.ugm.ac.id/126090/ KORELASI ANTIGEN NS1 KUANTITATIF TERHADAP DERAJAT KEPARAHAN INFEKSI DENGUE , Ni Made Adi Purnami , Prof. dr. Mohammad Juffrie, Ph.D, Sp.A(K) ETD Dengue infection is one of the main causes of morbidity and mortality of children in Indonesia. Since it is known that earlier treatment and supportive therapies can decreased case fatality rate from DHF, identification of the person who has risk to develop to DHF must be quickly found mainly in areas of endemic. The purpose of these studies is to find a correlation between increase of quantitative sNS with clinical history of severe dengue infection, and also to determine the cutt off point of quantitative sNS1 with the probability severe dengue infection. This research is a cross-sectional study conducted on children with dengue infection in Tropical Infections Division of The children's Health Department, Denpasar. Detection of the antigen is made by examining sNS1 immuno-assay. Analysis correlation of Spearman test used to look the relationship between increased quantitative sNS1 with clinical history of severe dengue. ROC curve and the AUC used to determine the cutt off point of quantitative sNS1 with the probability severe dengue infection. This research found a strong positive relationship between sNS1and clinical history of severe dengue with a value of r = 0.903, p<0.001. Spearman analysis showed that increased sNS1 have positive correlation with severe dengue infection. [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , Ni Made Adi Purnami and , Prof. dr. Mohammad Juffrie, Ph.D, Sp.A(K) (2013) KORELASI ANTIGEN NS1 KUANTITATIF TERHADAP DERAJAT KEPARAHAN INFEKSI DENGUE. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=66282
spellingShingle ETD
, Ni Made Adi Purnami
, Prof. dr. Mohammad Juffrie, Ph.D, Sp.A(K)
KORELASI ANTIGEN NS1 KUANTITATIF TERHADAP DERAJAT KEPARAHAN INFEKSI DENGUE
title KORELASI ANTIGEN NS1 KUANTITATIF TERHADAP DERAJAT KEPARAHAN INFEKSI DENGUE
title_full KORELASI ANTIGEN NS1 KUANTITATIF TERHADAP DERAJAT KEPARAHAN INFEKSI DENGUE
title_fullStr KORELASI ANTIGEN NS1 KUANTITATIF TERHADAP DERAJAT KEPARAHAN INFEKSI DENGUE
title_full_unstemmed KORELASI ANTIGEN NS1 KUANTITATIF TERHADAP DERAJAT KEPARAHAN INFEKSI DENGUE
title_short KORELASI ANTIGEN NS1 KUANTITATIF TERHADAP DERAJAT KEPARAHAN INFEKSI DENGUE
title_sort korelasi antigen ns1 kuantitatif terhadap derajat keparahan infeksi dengue
topic ETD
work_keys_str_mv AT nimadeadipurnami korelasiantigenns1kuantitatifterhadapderajatkeparahaninfeksidengue
AT profdrmohammadjuffriephdspak korelasiantigenns1kuantitatifterhadapderajatkeparahaninfeksidengue