EFEK ANTIINFLAMASI EKSTRAK AIR SARANG BURUNG WALET (Collocalia fuciphaga Thunberg, 1812) PADA MENCIT (Mus musculus L. 1758) YANG DIINDUKSI KARAGENAN
Swiftlets Collocalia fuciphaga constructed their nest with salivary glue. The nest is white and called Edible Bird�s Nest (EBN). The major component of EBN is glycoproteins that consist of sialic acid (9 %), N-acetylgalactosamine (7.2 %), N-acetylglucosamine (5.3 %), galactose (16.9 %) and fructos...
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| Format: | Thesis |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2013
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| _version_ | 1826047603052118016 |
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| author | , FITRI NUROINI , Dr. biol. hom. Nastiti Wijayanti, M.Si. |
| author_facet | , FITRI NUROINI , Dr. biol. hom. Nastiti Wijayanti, M.Si. |
| author_sort | , FITRI NUROINI |
| collection | UGM |
| description | Swiftlets Collocalia fuciphaga constructed their nest with salivary glue. The
nest is white and called Edible Bird�s Nest (EBN). The major component of EBN
is glycoproteins that consist of sialic acid (9 %), N-acetylgalactosamine (7.2 %),
N-acetylglucosamine (5.3 %), galactose (16.9 %) and fructose (0.7 %).
Glycoprotein is an important molecule in the regulation of the immune system,
increase cell proliferation and decrease the production of TNF-α. The aims of this
study was to determine the anti-inflammatory effect of EBN swiftlet C. fuciphaga
in the expression of TNF-α, histological and integumentum feet thick, total
leukocyte count and leukocyte differential count. Research design using
Randomized Complete Design (RCD) with 6 treatment and 4 replication. The
treatment are normal control, negative control, antiinflammation control group
and 3 group treatment with EBN extract (0.1, 1 and 10 mg/ 20 g W. EBN was
given orally and after an hour each group were injected subcutaneously with 0.05
ml of 1 % carrageenan in 0.9 % NaCl on the right foot mice. The results showed
that administration of oral EBN inhibit carrageenan-induced inflammation.
Inhibition of TNF-α production showed by decrease the value of TNF-α ratio.
Administration EBN orally was decresed total leukocyte count and leukocyte
differential count, mainly lymphocyte and basophil. On the other hand, EBN
hasn�t effect integumentum thick legs of mice, directly |
| first_indexed | 2024-03-13T23:13:25Z |
| format | Thesis |
| id | oai:generic.eprints.org:126314 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T23:13:25Z |
| publishDate | 2013 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1263142016-03-04T08:36:09Z https://repository.ugm.ac.id/126314/ EFEK ANTIINFLAMASI EKSTRAK AIR SARANG BURUNG WALET (Collocalia fuciphaga Thunberg, 1812) PADA MENCIT (Mus musculus L. 1758) YANG DIINDUKSI KARAGENAN , FITRI NUROINI , Dr. biol. hom. Nastiti Wijayanti, M.Si. ETD Swiftlets Collocalia fuciphaga constructed their nest with salivary glue. The nest is white and called Edible Bird�s Nest (EBN). The major component of EBN is glycoproteins that consist of sialic acid (9 %), N-acetylgalactosamine (7.2 %), N-acetylglucosamine (5.3 %), galactose (16.9 %) and fructose (0.7 %). Glycoprotein is an important molecule in the regulation of the immune system, increase cell proliferation and decrease the production of TNF-α. The aims of this study was to determine the anti-inflammatory effect of EBN swiftlet C. fuciphaga in the expression of TNF-α, histological and integumentum feet thick, total leukocyte count and leukocyte differential count. Research design using Randomized Complete Design (RCD) with 6 treatment and 4 replication. The treatment are normal control, negative control, antiinflammation control group and 3 group treatment with EBN extract (0.1, 1 and 10 mg/ 20 g W. EBN was given orally and after an hour each group were injected subcutaneously with 0.05 ml of 1 % carrageenan in 0.9 % NaCl on the right foot mice. The results showed that administration of oral EBN inhibit carrageenan-induced inflammation. Inhibition of TNF-α production showed by decrease the value of TNF-α ratio. Administration EBN orally was decresed total leukocyte count and leukocyte differential count, mainly lymphocyte and basophil. On the other hand, EBN hasn�t effect integumentum thick legs of mice, directly [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , FITRI NUROINI and , Dr. biol. hom. Nastiti Wijayanti, M.Si. (2013) EFEK ANTIINFLAMASI EKSTRAK AIR SARANG BURUNG WALET (Collocalia fuciphaga Thunberg, 1812) PADA MENCIT (Mus musculus L. 1758) YANG DIINDUKSI KARAGENAN. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=66533 |
| spellingShingle | ETD , FITRI NUROINI , Dr. biol. hom. Nastiti Wijayanti, M.Si. EFEK ANTIINFLAMASI EKSTRAK AIR SARANG BURUNG WALET (Collocalia fuciphaga Thunberg, 1812) PADA MENCIT (Mus musculus L. 1758) YANG DIINDUKSI KARAGENAN |
| title | EFEK ANTIINFLAMASI EKSTRAK AIR SARANG BURUNG WALET (Collocalia fuciphaga
Thunberg, 1812) PADA MENCIT (Mus musculus L. 1758) YANG DIINDUKSI KARAGENAN |
| title_full | EFEK ANTIINFLAMASI EKSTRAK AIR SARANG BURUNG WALET (Collocalia fuciphaga
Thunberg, 1812) PADA MENCIT (Mus musculus L. 1758) YANG DIINDUKSI KARAGENAN |
| title_fullStr | EFEK ANTIINFLAMASI EKSTRAK AIR SARANG BURUNG WALET (Collocalia fuciphaga
Thunberg, 1812) PADA MENCIT (Mus musculus L. 1758) YANG DIINDUKSI KARAGENAN |
| title_full_unstemmed | EFEK ANTIINFLAMASI EKSTRAK AIR SARANG BURUNG WALET (Collocalia fuciphaga
Thunberg, 1812) PADA MENCIT (Mus musculus L. 1758) YANG DIINDUKSI KARAGENAN |
| title_short | EFEK ANTIINFLAMASI EKSTRAK AIR SARANG BURUNG WALET (Collocalia fuciphaga
Thunberg, 1812) PADA MENCIT (Mus musculus L. 1758) YANG DIINDUKSI KARAGENAN |
| title_sort | efek antiinflamasi ekstrak air sarang burung walet collocalia fuciphaga thunberg 1812 pada mencit mus musculus l 1758 yang diinduksi karagenan |
| topic | ETD |
| work_keys_str_mv | AT fitrinuroini efekantiinflamasiekstrakairsarangburungwaletcollocaliafuciphagathunberg1812padamencitmusmusculusl1758yangdiinduksikaragenan AT drbiolhomnastitiwijayantimsi efekantiinflamasiekstrakairsarangburungwaletcollocaliafuciphagathunberg1812padamencitmusmusculusl1758yangdiinduksikaragenan |