HUBUNGAN ANTARA KADAR TSH SERUM DAN INDEKS MASSA TUBUH PADA WANITA USIA SUBUR DENGAN HIPOTIROID DI KABUPATEN PURWOREJO JAWA TENGAH

Background: Iodine Deficiency Disorders (IDD) is the main nutrition problem in Indonesia. Iodine Deficiency Disorders can affect mental development and intelligence level that decreases human resources quality. The most common IDD is hypothyroid. In hypothyroid, thyroid hormones levels are low and T...

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Bibliographic Details
Main Authors: , THERESIA KANIA, , Dra. Tasmini, M.Kes
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2014
Subjects:
ETD
Description
Summary:Background: Iodine Deficiency Disorders (IDD) is the main nutrition problem in Indonesia. Iodine Deficiency Disorders can affect mental development and intelligence level that decreases human resources quality. The most common IDD is hypothyroid. In hypothyroid, thyroid hormones levels are low and TSH levels are high, this condition can affect BMI (Body Mass Index) by Basal Metabolic Rate (BMR) modification. Cretinism, extreme clinical manifestation of IDD, is a condition of severely stunted physical and mental growth. Objective: To discover relation between TSH serum levels and BMI on reproductive-age women with hypothyroid in Purworejo, Central Java. Method: This study uses case-control study. ELISA method was used for determination of serum TSH. Case group is reproductive-age women with hypothyroid (serum TSH � 3.0 µIU/mL) and control group is reproductive-age women with euthyroid (serum TSH<3.0 µIU/mL). Result: Mean height in reproductive-age women with hypothyroid was 150.39±6.63 cm, mean height in reproductive-age women with euthyroid was 150.67±5.26 cm, there were no significance differences between groups (p=0.93). Mean weight in reproductive-age women with hypothyroid was 52.83±8.05 kg, mean height in reproductive-age women with euthyroid was 52.65±9.92 kg, there were no significance differences between groups (p=0.86). Mean BMI in reproductive-age women with hypothyroid was 22.91±3.78 kg/m 2 , mean BMI in reproductive-age women with euthyroid was 23.05±4.02 kg/m 2 , there were no significance differences between groups (p=0,44). There was weak positive correlation correlation between BMI and serum TSH in reproductiveage women with hypothyroid which was not statiscally significance (r=0.094