Summary: | Background: Iodine Deficiency Disorders (IDD) is the
main nutrition problem in Indonesia. Iodine Deficiency
Disorders can affect mental development and
intelligence level that decreases human resources
quality. The most common IDD is hypothyroid. In
hypothyroid, thyroid hormones levels are low and TSH
levels are high, this condition can affect BMI (Body
Mass Index) by Basal Metabolic Rate (BMR) modification.
Cretinism, extreme clinical manifestation of IDD, is a
condition of severely stunted physical and mental
growth.
Objective: To discover relation between TSH serum
levels and BMI on reproductive-age women with
hypothyroid in Purworejo, Central Java.
Method: This study uses case-control study. ELISA
method was used for determination of serum TSH. Case
group is reproductive-age women with hypothyroid (serum
TSH � 3.0 µIU/mL) and control group is reproductive-age
women with euthyroid (serum TSH<3.0 µIU/mL).
Result: Mean height in reproductive-age women with
hypothyroid was 150.39±6.63 cm, mean height in
reproductive-age women with euthyroid was 150.67±5.26
cm, there were no significance differences between
groups (p=0.93). Mean weight in reproductive-age women
with hypothyroid was 52.83±8.05 kg, mean height in
reproductive-age women with euthyroid was 52.65±9.92
kg, there were no significance differences between
groups (p=0.86). Mean BMI in reproductive-age women
with hypothyroid was 22.91±3.78 kg/m
2
, mean BMI in
reproductive-age women with euthyroid was 23.05±4.02
kg/m
2
, there were no significance differences between
groups (p=0,44). There was weak positive correlation
correlation between BMI and serum TSH in reproductiveage
women with hypothyroid which was not statiscally
significance (r=0.094
|