KORELASI SERUM AMYLOID A (SAA) DENGAN KADAR TROPONIN I PADA PASIEN SINDROMA KORONER AKUT DI RSUP DR.SARDJITO YOGYAKARTA
Background : Acute Coronary Syndrome (ACS) is a multifactorial disease and occurs in response inflammation, plaque rupture and cause thrombosis of blood vessels either in total or in part. Biomarkers play an important role in the diagnosis and treatment will be given. Serum amyloid A is an acute inf...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2014
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| Summary: | Background : Acute Coronary Syndrome (ACS) is a
multifactorial disease and occurs in response
inflammation, plaque rupture and cause thrombosis of
blood vessels either in total or in part. Biomarkers play
an important role in the diagnosis and treatment will be
given. Serum amyloid A is an acute inflammasi marker that
acts to stimulate the expression of matrix degrading
enzymes that can cause plaque rupture. Troponin I is a
marker of heart muscle damage due to necrosis.
Objective : to known the correlation between serum
amyloid A and Troponin I levels in patients with Acute
Coronary Syndrome .
Methods : The study design was a cross sectional study
of patients with acute coronary syndrome subjects
received treatment in ICCU Hospital Dr.Sardjito.
Examination of SAA was measured by sandwich ELISA method
whereas Troponin-I conducted by ELISA using a VIDAS
Troponin I Ultra then analyzed with Spearman's test.
Results : There were 33 patients withACS . From the
analysis of the data using the Spearman test ,there are
not significant correlations between the SAA and Troponin
I in patient with ACS (r=0.6, p=0.74).
Conclusions : There are not significant correlation
between SAA and Troponin I in patients with ACS in ICCU
Dr . Sardjito Yogyakarta. |
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