| Summary: | Background : Acute kidney injury (AKI) causes high mortality and often
undiagnosed. AKI (Acute Kidney Injury) could be predicted using RIFLE (Risk-
Injury-Failure-Loss-End Stage renal failure) criteria. Incidence of AKI among
critical ill patients is quite high. AKI is a new terminology of acute renal failure.
This terminology can explain all stages of renal injury from early stage up to renal
failure. This terminology is used to recognize earlier renal disfunction. AKI used
urine output and plasma creatinin as parameters of renal injury. Aim of this study
to know that sepsis, hypovolemia, hypotension, cardiac surgery, diabetes mellitus
(DM), age more than 60 years old, nefrotoxic agents, congestive heart failure, and
severe eclampsy are risk factors of AKI of patients in ICU RSUP dr. Sardjito,
Yogyakarta.
Methode : Cohort retrospective study. Subjects of this study about 121 patients
admitted to ICU RSUP dr. sardjito from January up to march 2013. All of the
patients have complete data during in care at ICU. No congestive heart failure
patient were recruited in this study.
Result : This study shows that hypotension (RR 18,46, p value 0,0001), severe
eclampsy (RR 15,85, p value 0,0001), and sepsis (RR 5,32, p value 0,001) are
independent and strong risk factors for incidence of AKI in patients which in care
at ICU RSUP dr Sardjito. Hypovolemia, nefrotoxic agents, and age more than 60
years old are also risk factors for AKI. Diabetes mellitus with no complication and
cardiac surgery are not risk factors for AKI.
Conclusion : Hypotension, severe eclampsy, and sepsis are independent and
strong risk factors for incidence of AKI in patients which in care at ICU RSUP dr
Sardjito. Hypovolemia, nefrotoxic agents, and age more than 60 years old are also
risk factors for AKI. Diabetes mellitus with no complication and cardiac surgery
are not risk factors for AKI.
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