THE DIFFERENCE OF ALKALINE PHOSPHATASE, BILIRUBIN,AND GAMMA GLUTAMYL TRANSFERASE LEVEL IN DIFFERENT GALLSTONE LOCATION OF GALLSTONE PATIENT IN RSUP DR SARDJITO.
Background : In daily practice, it is difficult to differentiate between cholelithiasis and choledocholithiasis patients by clinical symptoms. Even though obstructive jaundice usually happen in choledocholithiasis, but it can also being absence. This problem can lead to underdiagnosis and cause the...
| Hoofdauteurs: | , |
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| Formaat: | Thesis |
| Gepubliceerd in: |
[Yogyakarta] : Universitas Gadjah Mada
2014
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| Onderwerpen: |
| _version_ | 1826047962268041216 |
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| author | , SARAH MARDHIAH BINTI SUDIN , dr. Catharina Triwikatmani, M.Kes, SpPD |
| author_facet | , SARAH MARDHIAH BINTI SUDIN , dr. Catharina Triwikatmani, M.Kes, SpPD |
| author_sort | , SARAH MARDHIAH BINTI SUDIN |
| collection | UGM |
| description | Background : In daily practice, it is difficult to
differentiate between cholelithiasis and choledocholithiasis
patients by clinical symptoms. Even though obstructive
jaundice usually happen in choledocholithiasis, but it can
also being absence. This problem can lead to underdiagnosis
and cause the stone to be remain in the bile duct even after
operation. The biochemical testing such as bilirubin,
alkaline phosphatase and gamma glutamyl transferase can
indicate biliary obstruction.
Aim : The aim is to evaluate the difference in biochemical
marker which are bilirubin, alkaline phosphatase and gamma
glutamyl transferase at different gallstone locations in
cholelithiasis and choledocholithiasis patients.
Method : 88 patients from surgery department are selected for
this research. The subjects are divided into two groups which
are patients with choledocholithiasis (n=11) and
cholelithiasis (n=77). For total bilirubin, 75 cholelithiasis
and 11 choledocholithiasis are selected. While 28
cholelithiasis and 7 choledocholithiasis patients for
difference in alkaline phosphatase and 18 cholelithiasis and
7 choledocholithiasis patients for difference in Gamma
Glutamyl Transferase. The liver marker level were taken
maximum one week before the operation.
Results : Significant different was found in Bilirubin and
ALP P < 0.05 . Overall, the median shows that the level of
Bilirubin and ALP is higher in choledocholithiasis if compared
with cholelithiasis patients. While no significant different
in Gamma Glutamyl Transferase was found P > 0.05. Eventhough
overall median results shows that the level of GGT in
choledocholithiasis is higher than in cholelithiasis but some
low ranks and some high ranks will occur in each group, that
is the ranks will be distributed across the two group which
are cholelithiasis and choledocholithiasis more or less
evenly.
Conclusion : In a conclusion, only bilirubin and alkaline
phosphatase level have a significant difference in different
gallstone location. |
| first_indexed | 2024-03-13T23:19:40Z |
| format | Thesis |
| id | oai:generic.eprints.org:128114 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T23:19:40Z |
| publishDate | 2014 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1281142016-03-04T08:11:56Z https://repository.ugm.ac.id/128114/ THE DIFFERENCE OF ALKALINE PHOSPHATASE, BILIRUBIN,AND GAMMA GLUTAMYL TRANSFERASE LEVEL IN DIFFERENT GALLSTONE LOCATION OF GALLSTONE PATIENT IN RSUP DR SARDJITO. , SARAH MARDHIAH BINTI SUDIN , dr. Catharina Triwikatmani, M.Kes, SpPD ETD Background : In daily practice, it is difficult to differentiate between cholelithiasis and choledocholithiasis patients by clinical symptoms. Even though obstructive jaundice usually happen in choledocholithiasis, but it can also being absence. This problem can lead to underdiagnosis and cause the stone to be remain in the bile duct even after operation. The biochemical testing such as bilirubin, alkaline phosphatase and gamma glutamyl transferase can indicate biliary obstruction. Aim : The aim is to evaluate the difference in biochemical marker which are bilirubin, alkaline phosphatase and gamma glutamyl transferase at different gallstone locations in cholelithiasis and choledocholithiasis patients. Method : 88 patients from surgery department are selected for this research. The subjects are divided into two groups which are patients with choledocholithiasis (n=11) and cholelithiasis (n=77). For total bilirubin, 75 cholelithiasis and 11 choledocholithiasis are selected. While 28 cholelithiasis and 7 choledocholithiasis patients for difference in alkaline phosphatase and 18 cholelithiasis and 7 choledocholithiasis patients for difference in Gamma Glutamyl Transferase. The liver marker level were taken maximum one week before the operation. Results : Significant different was found in Bilirubin and ALP P < 0.05 . Overall, the median shows that the level of Bilirubin and ALP is higher in choledocholithiasis if compared with cholelithiasis patients. While no significant different in Gamma Glutamyl Transferase was found P > 0.05. Eventhough overall median results shows that the level of GGT in choledocholithiasis is higher than in cholelithiasis but some low ranks and some high ranks will occur in each group, that is the ranks will be distributed across the two group which are cholelithiasis and choledocholithiasis more or less evenly. Conclusion : In a conclusion, only bilirubin and alkaline phosphatase level have a significant difference in different gallstone location. [Yogyakarta] : Universitas Gadjah Mada 2014 Thesis NonPeerReviewed , SARAH MARDHIAH BINTI SUDIN and , dr. Catharina Triwikatmani, M.Kes, SpPD (2014) THE DIFFERENCE OF ALKALINE PHOSPHATASE, BILIRUBIN,AND GAMMA GLUTAMYL TRANSFERASE LEVEL IN DIFFERENT GALLSTONE LOCATION OF GALLSTONE PATIENT IN RSUP DR SARDJITO. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=68445 |
| spellingShingle | ETD , SARAH MARDHIAH BINTI SUDIN , dr. Catharina Triwikatmani, M.Kes, SpPD THE DIFFERENCE OF ALKALINE PHOSPHATASE, BILIRUBIN,AND GAMMA GLUTAMYL TRANSFERASE LEVEL IN DIFFERENT GALLSTONE LOCATION OF GALLSTONE PATIENT IN RSUP DR SARDJITO. |
| title | THE DIFFERENCE OF ALKALINE PHOSPHATASE, BILIRUBIN,AND GAMMA GLUTAMYL TRANSFERASE LEVEL IN
DIFFERENT GALLSTONE LOCATION OF GALLSTONE PATIENT IN RSUP DR SARDJITO. |
| title_full | THE DIFFERENCE OF ALKALINE PHOSPHATASE, BILIRUBIN,AND GAMMA GLUTAMYL TRANSFERASE LEVEL IN
DIFFERENT GALLSTONE LOCATION OF GALLSTONE PATIENT IN RSUP DR SARDJITO. |
| title_fullStr | THE DIFFERENCE OF ALKALINE PHOSPHATASE, BILIRUBIN,AND GAMMA GLUTAMYL TRANSFERASE LEVEL IN
DIFFERENT GALLSTONE LOCATION OF GALLSTONE PATIENT IN RSUP DR SARDJITO. |
| title_full_unstemmed | THE DIFFERENCE OF ALKALINE PHOSPHATASE, BILIRUBIN,AND GAMMA GLUTAMYL TRANSFERASE LEVEL IN
DIFFERENT GALLSTONE LOCATION OF GALLSTONE PATIENT IN RSUP DR SARDJITO. |
| title_short | THE DIFFERENCE OF ALKALINE PHOSPHATASE, BILIRUBIN,AND GAMMA GLUTAMYL TRANSFERASE LEVEL IN
DIFFERENT GALLSTONE LOCATION OF GALLSTONE PATIENT IN RSUP DR SARDJITO. |
| title_sort | difference of alkaline phosphatase bilirubin and gamma glutamyl transferase level in different gallstone location of gallstone patient in rsup dr sardjito |
| topic | ETD |
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