HUBUNGAN ANTARA FRAGMENTASI DNA SPERMA DAN VIABILITAS SPERMA PADA KASUS INFERTILITAS PRIA
Background : Infertility affects 10-15% of the couples of reproductive age in the world. The male factor contributes 40-50% of infertility cases. WHO routine sperm analysis can provide a limited prediction of male fertility potential and is not always able to explain the cause of male infertility. I...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2014
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| author | , LAILATUSSAADAH , Prof. dr. Djaswadi Dasuki, Sp.OG., MPH., Ph.D. |
| author_facet | , LAILATUSSAADAH , Prof. dr. Djaswadi Dasuki, Sp.OG., MPH., Ph.D. |
| author_sort | , LAILATUSSAADAH |
| collection | UGM |
| description | Background : Infertility affects 10-15% of the couples of
reproductive age in the world. The male factor contributes
40-50% of infertility cases. WHO routine sperm analysis can
provide a limited prediction of male fertility potential and
is not always able to explain the cause of male infertility.
In addition to assessing sperm viability, sperm DNA
integrity test is important to be performed in infertile
patients. Unfortunately, the correlation between both of
them haven�t been understood clearly.
Objective : This study was made specifically to determine
the relationship between sperm DNA fragmentation and sperm
viability in the male infertility cases. In this study,
seminal leukocyte also counted as the confounding variable.
Methods : The study was performed using analytical
observational with cross-sectional method. Subjects were 28
men with infertility complaints. Data were obtained from
medical Record at Permata Hati Clinic, RSUP dr.Sardjito,
Yogyakarta.
Results : There was a negative correlation between sperm DNA
fragmentation and sperm viability, where the bivariate
analysis using Chi-square method showed a statistically
significant result (P=0.02). Multivariate analysis using
logistic regression also showed a significant associated
result between sperm DNA fragmentation and sperm viability,
even after the confounding variable was included, namely
semen leukocyte count, the results obtained remained
associated significantly (OR= 7.31 |
| first_indexed | 2024-03-13T23:20:30Z |
| format | Thesis |
| id | oai:generic.eprints.org:128308 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T23:20:30Z |
| publishDate | 2014 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1283082016-03-04T07:58:10Z https://repository.ugm.ac.id/128308/ HUBUNGAN ANTARA FRAGMENTASI DNA SPERMA DAN VIABILITAS SPERMA PADA KASUS INFERTILITAS PRIA , LAILATUSSAADAH , Prof. dr. Djaswadi Dasuki, Sp.OG., MPH., Ph.D. ETD Background : Infertility affects 10-15% of the couples of reproductive age in the world. The male factor contributes 40-50% of infertility cases. WHO routine sperm analysis can provide a limited prediction of male fertility potential and is not always able to explain the cause of male infertility. In addition to assessing sperm viability, sperm DNA integrity test is important to be performed in infertile patients. Unfortunately, the correlation between both of them haven�t been understood clearly. Objective : This study was made specifically to determine the relationship between sperm DNA fragmentation and sperm viability in the male infertility cases. In this study, seminal leukocyte also counted as the confounding variable. Methods : The study was performed using analytical observational with cross-sectional method. Subjects were 28 men with infertility complaints. Data were obtained from medical Record at Permata Hati Clinic, RSUP dr.Sardjito, Yogyakarta. Results : There was a negative correlation between sperm DNA fragmentation and sperm viability, where the bivariate analysis using Chi-square method showed a statistically significant result (P=0.02). Multivariate analysis using logistic regression also showed a significant associated result between sperm DNA fragmentation and sperm viability, even after the confounding variable was included, namely semen leukocyte count, the results obtained remained associated significantly (OR= 7.31 [Yogyakarta] : Universitas Gadjah Mada 2014 Thesis NonPeerReviewed , LAILATUSSAADAH and , Prof. dr. Djaswadi Dasuki, Sp.OG., MPH., Ph.D. (2014) HUBUNGAN ANTARA FRAGMENTASI DNA SPERMA DAN VIABILITAS SPERMA PADA KASUS INFERTILITAS PRIA. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=68648 |
| spellingShingle | ETD , LAILATUSSAADAH , Prof. dr. Djaswadi Dasuki, Sp.OG., MPH., Ph.D. HUBUNGAN ANTARA FRAGMENTASI DNA SPERMA DAN VIABILITAS SPERMA PADA KASUS INFERTILITAS PRIA |
| title | HUBUNGAN ANTARA FRAGMENTASI DNA SPERMA DAN VIABILITAS
SPERMA PADA KASUS INFERTILITAS PRIA |
| title_full | HUBUNGAN ANTARA FRAGMENTASI DNA SPERMA DAN VIABILITAS
SPERMA PADA KASUS INFERTILITAS PRIA |
| title_fullStr | HUBUNGAN ANTARA FRAGMENTASI DNA SPERMA DAN VIABILITAS
SPERMA PADA KASUS INFERTILITAS PRIA |
| title_full_unstemmed | HUBUNGAN ANTARA FRAGMENTASI DNA SPERMA DAN VIABILITAS
SPERMA PADA KASUS INFERTILITAS PRIA |
| title_short | HUBUNGAN ANTARA FRAGMENTASI DNA SPERMA DAN VIABILITAS
SPERMA PADA KASUS INFERTILITAS PRIA |
| title_sort | hubungan antara fragmentasi dna sperma dan viabilitas sperma pada kasus infertilitas pria |
| topic | ETD |
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