EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS
Introduction: The development of economically affordable bonegraft is needed for orthopaedic practice. Synthetic phorous biphasic calcium phosphate could be produced from bovine bone. Objective: To evaluate the application of phorous bovine biphasic calcium phosphate compared to commercial phorous h...
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Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2014
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author | , DIAH BUDIASIH , Dr. dr. Rahadyan Magetsari,Sp.OT(K), Ph.D, FICS |
author_facet | , DIAH BUDIASIH , Dr. dr. Rahadyan Magetsari,Sp.OT(K), Ph.D, FICS |
author_sort | , DIAH BUDIASIH |
collection | UGM |
description | Introduction: The development of economically
affordable bonegraft is needed for orthopaedic
practice. Synthetic phorous biphasic calcium phosphate
could be produced from bovine bone.
Objective: To evaluate the application of phorous
bovine biphasic calcium phosphate compared to
commercial phorous hydroxyapatite graft as bonegraft on
animal model.
Methods: This study comprise of graft manufacturing
process using bovine bone as calcium resource for
phorous biphasic calcium phosphate production. Graft
implantation procedure of researched material and
commercial hydroxtapatite was conducted on twenty
critical size defect of Rattus novergicus femur. X-Ray
evaluation was performed at the day of implantation and
at teh 28 days after implantation. All rats were killed
at 4th week after surgery.
Result: After thermal heating process up to 1300°C, we
have managed to form biphasic calcium phosphate. The
following animal implantation also showed no
significant difference on radiologic (ISOLS) score
compare to the commercial graft based on Mann Whitney U
test with p = 0,536 (p > 0, 05).
Conclusion: Phorous bovine biphasic calcium phosphate
graft has equal outcome on bone healing with regards to
the commercial porous hydroxyapatite graft. |
first_indexed | 2024-03-13T23:20:33Z |
format | Thesis |
id | oai:generic.eprints.org:128326 |
institution | Universiti Gadjah Mada |
last_indexed | 2024-03-13T23:20:33Z |
publishDate | 2014 |
publisher | [Yogyakarta] : Universitas Gadjah Mada |
record_format | dspace |
spelling | oai:generic.eprints.org:1283262016-03-04T07:54:47Z https://repository.ugm.ac.id/128326/ EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS , DIAH BUDIASIH , Dr. dr. Rahadyan Magetsari,Sp.OT(K), Ph.D, FICS ETD Introduction: The development of economically affordable bonegraft is needed for orthopaedic practice. Synthetic phorous biphasic calcium phosphate could be produced from bovine bone. Objective: To evaluate the application of phorous bovine biphasic calcium phosphate compared to commercial phorous hydroxyapatite graft as bonegraft on animal model. Methods: This study comprise of graft manufacturing process using bovine bone as calcium resource for phorous biphasic calcium phosphate production. Graft implantation procedure of researched material and commercial hydroxtapatite was conducted on twenty critical size defect of Rattus novergicus femur. X-Ray evaluation was performed at the day of implantation and at teh 28 days after implantation. All rats were killed at 4th week after surgery. Result: After thermal heating process up to 1300°C, we have managed to form biphasic calcium phosphate. The following animal implantation also showed no significant difference on radiologic (ISOLS) score compare to the commercial graft based on Mann Whitney U test with p = 0,536 (p > 0, 05). Conclusion: Phorous bovine biphasic calcium phosphate graft has equal outcome on bone healing with regards to the commercial porous hydroxyapatite graft. [Yogyakarta] : Universitas Gadjah Mada 2014 Thesis NonPeerReviewed , DIAH BUDIASIH and , Dr. dr. Rahadyan Magetsari,Sp.OT(K), Ph.D, FICS (2014) EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=68666 |
spellingShingle | ETD , DIAH BUDIASIH , Dr. dr. Rahadyan Magetsari,Sp.OT(K), Ph.D, FICS EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS |
title | EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS |
title_full | EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS |
title_fullStr | EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS |
title_full_unstemmed | EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS |
title_short | EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS |
title_sort | evaluasi in vivo phorous bovine biphasic calcium phosphate sebagai bahan substitusi gap tulang pada rattus novergicus |
topic | ETD |
work_keys_str_mv | AT diahbudiasih evaluasiinvivophorousbovinebiphasiccalciumphosphatesebagaibahansubstitusigaptulangpadarattusnovergicus AT drdrrahadyanmagetsarispotkphdfics evaluasiinvivophorousbovinebiphasiccalciumphosphatesebagaibahansubstitusigaptulangpadarattusnovergicus |