EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS

Introduction: The development of economically affordable bonegraft is needed for orthopaedic practice. Synthetic phorous biphasic calcium phosphate could be produced from bovine bone. Objective: To evaluate the application of phorous bovine biphasic calcium phosphate compared to commercial phorous h...

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Main Authors: , DIAH BUDIASIH, , Dr. dr. Rahadyan Magetsari,Sp.OT(K), Ph.D, FICS
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2014
Subjects:
ETD
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author , DIAH BUDIASIH
, Dr. dr. Rahadyan Magetsari,Sp.OT(K), Ph.D, FICS
author_facet , DIAH BUDIASIH
, Dr. dr. Rahadyan Magetsari,Sp.OT(K), Ph.D, FICS
author_sort , DIAH BUDIASIH
collection UGM
description Introduction: The development of economically affordable bonegraft is needed for orthopaedic practice. Synthetic phorous biphasic calcium phosphate could be produced from bovine bone. Objective: To evaluate the application of phorous bovine biphasic calcium phosphate compared to commercial phorous hydroxyapatite graft as bonegraft on animal model. Methods: This study comprise of graft manufacturing process using bovine bone as calcium resource for phorous biphasic calcium phosphate production. Graft implantation procedure of researched material and commercial hydroxtapatite was conducted on twenty critical size defect of Rattus novergicus femur. X-Ray evaluation was performed at the day of implantation and at teh 28 days after implantation. All rats were killed at 4th week after surgery. Result: After thermal heating process up to 1300°C, we have managed to form biphasic calcium phosphate. The following animal implantation also showed no significant difference on radiologic (ISOLS) score compare to the commercial graft based on Mann Whitney U test with p = 0,536 (p > 0, 05). Conclusion: Phorous bovine biphasic calcium phosphate graft has equal outcome on bone healing with regards to the commercial porous hydroxyapatite graft.
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spelling oai:generic.eprints.org:1283262016-03-04T07:54:47Z https://repository.ugm.ac.id/128326/ EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS , DIAH BUDIASIH , Dr. dr. Rahadyan Magetsari,Sp.OT(K), Ph.D, FICS ETD Introduction: The development of economically affordable bonegraft is needed for orthopaedic practice. Synthetic phorous biphasic calcium phosphate could be produced from bovine bone. Objective: To evaluate the application of phorous bovine biphasic calcium phosphate compared to commercial phorous hydroxyapatite graft as bonegraft on animal model. Methods: This study comprise of graft manufacturing process using bovine bone as calcium resource for phorous biphasic calcium phosphate production. Graft implantation procedure of researched material and commercial hydroxtapatite was conducted on twenty critical size defect of Rattus novergicus femur. X-Ray evaluation was performed at the day of implantation and at teh 28 days after implantation. All rats were killed at 4th week after surgery. Result: After thermal heating process up to 1300°C, we have managed to form biphasic calcium phosphate. The following animal implantation also showed no significant difference on radiologic (ISOLS) score compare to the commercial graft based on Mann Whitney U test with p = 0,536 (p > 0, 05). Conclusion: Phorous bovine biphasic calcium phosphate graft has equal outcome on bone healing with regards to the commercial porous hydroxyapatite graft. [Yogyakarta] : Universitas Gadjah Mada 2014 Thesis NonPeerReviewed , DIAH BUDIASIH and , Dr. dr. Rahadyan Magetsari,Sp.OT(K), Ph.D, FICS (2014) EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=68666
spellingShingle ETD
, DIAH BUDIASIH
, Dr. dr. Rahadyan Magetsari,Sp.OT(K), Ph.D, FICS
EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS
title EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS
title_full EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS
title_fullStr EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS
title_full_unstemmed EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS
title_short EVALUASI IN VIVO PHOROUS BOVINE BIPHASIC CALCIUM PHOSPHATE SEBAGAI BAHAN SUBSTITUSI GAP TULANG PADA RATTUS NOVERGICUS
title_sort evaluasi in vivo phorous bovine biphasic calcium phosphate sebagai bahan substitusi gap tulang pada rattus novergicus
topic ETD
work_keys_str_mv AT diahbudiasih evaluasiinvivophorousbovinebiphasiccalciumphosphatesebagaibahansubstitusigaptulangpadarattusnovergicus
AT drdrrahadyanmagetsarispotkphdfics evaluasiinvivophorousbovinebiphasiccalciumphosphatesebagaibahansubstitusigaptulangpadarattusnovergicus