KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1 TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN METODE MICROBROTH DILUTION

Background: Fungus Infection especially Candida sp isolate, have a high mortality and morbidity in the world and Indonesia. Terbinafine as antifungal known cause resistance. The compound 1,10-Phenantroline has successfully differentiated to Phenantroline-1, which known have antibacterial and antipla...

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Main Authors: , WIWID SANTIKO, , dr. Titik Nuryastuti,Sp.MK. M.Si, Ph.D.
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2014
Subjects:
ETD
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author , WIWID SANTIKO
, dr. Titik Nuryastuti,Sp.MK. M.Si, Ph.D.
author_facet , WIWID SANTIKO
, dr. Titik Nuryastuti,Sp.MK. M.Si, Ph.D.
author_sort , WIWID SANTIKO
collection UGM
description Background: Fungus Infection especially Candida sp isolate, have a high mortality and morbidity in the world and Indonesia. Terbinafine as antifungal known cause resistance. The compound 1,10-Phenantroline has successfully differentiated to Phenantroline-1, which known have antibacterial and antiplasmodial effects. 1- 10,Phenantroline proved and binds to the metal complex form metal-phen complexes that bind to transtition metal ions, such as Cu2+, Mn2+ and Ag2+ and potentially as antifungal. Objective: To determine the potential of antifungal effect and Minimum Inhibitory Concentration (MIC) antifungal activity of Phenantrolin-1 against resistant strains of Candida sp with Terbinafine. Methods: Design of this study is descriptive experimental, used Microbroth Dilution method. Phenantrolin 1 with a concentration of 25
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institution Universiti Gadjah Mada
last_indexed 2024-03-13T23:21:05Z
publishDate 2014
publisher [Yogyakarta] : Universitas Gadjah Mada
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spelling oai:generic.eprints.org:1284742016-03-04T08:17:35Z https://repository.ugm.ac.id/128474/ KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1 TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN METODE MICROBROTH DILUTION , WIWID SANTIKO , dr. Titik Nuryastuti,Sp.MK. M.Si, Ph.D. ETD Background: Fungus Infection especially Candida sp isolate, have a high mortality and morbidity in the world and Indonesia. Terbinafine as antifungal known cause resistance. The compound 1,10-Phenantroline has successfully differentiated to Phenantroline-1, which known have antibacterial and antiplasmodial effects. 1- 10,Phenantroline proved and binds to the metal complex form metal-phen complexes that bind to transtition metal ions, such as Cu2+, Mn2+ and Ag2+ and potentially as antifungal. Objective: To determine the potential of antifungal effect and Minimum Inhibitory Concentration (MIC) antifungal activity of Phenantrolin-1 against resistant strains of Candida sp with Terbinafine. Methods: Design of this study is descriptive experimental, used Microbroth Dilution method. Phenantrolin 1 with a concentration of 25 [Yogyakarta] : Universitas Gadjah Mada 2014 Thesis NonPeerReviewed , WIWID SANTIKO and , dr. Titik Nuryastuti,Sp.MK. M.Si, Ph.D. (2014) KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1 TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN METODE MICROBROTH DILUTION. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=68821
spellingShingle ETD
, WIWID SANTIKO
, dr. Titik Nuryastuti,Sp.MK. M.Si, Ph.D.
KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1 TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN METODE MICROBROTH DILUTION
title KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1 TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN METODE MICROBROTH DILUTION
title_full KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1 TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN METODE MICROBROTH DILUTION
title_fullStr KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1 TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN METODE MICROBROTH DILUTION
title_full_unstemmed KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1 TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN METODE MICROBROTH DILUTION
title_short KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1 TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN METODE MICROBROTH DILUTION
title_sort kajian potensi antifungal senyawa fenantrolin 1 terhadap isolat candida sp resisten terbinafin dengan metode microbroth dilution
topic ETD
work_keys_str_mv AT wiwidsantiko kajianpotensiantifungalsenyawafenantrolin1terhadapisolatcandidaspresistenterbinafindenganmetodemicrobrothdilution
AT drtitiknuryastutispmkmsiphd kajianpotensiantifungalsenyawafenantrolin1terhadapisolatcandidaspresistenterbinafindenganmetodemicrobrothdilution