KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1 TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN METODE MICROBROTH DILUTION
Background: Fungus Infection especially Candida sp isolate, have a high mortality and morbidity in the world and Indonesia. Terbinafine as antifungal known cause resistance. The compound 1,10-Phenantroline has successfully differentiated to Phenantroline-1, which known have antibacterial and antipla...
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Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2014
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author | , WIWID SANTIKO , dr. Titik Nuryastuti,Sp.MK. M.Si, Ph.D. |
author_facet | , WIWID SANTIKO , dr. Titik Nuryastuti,Sp.MK. M.Si, Ph.D. |
author_sort | , WIWID SANTIKO |
collection | UGM |
description | Background: Fungus Infection especially Candida sp isolate,
have a high mortality and morbidity in the world and
Indonesia. Terbinafine as antifungal known cause
resistance. The compound 1,10-Phenantroline has
successfully differentiated to Phenantroline-1, which known
have antibacterial and antiplasmodial effects. 1-
10,Phenantroline proved and binds to the metal complex form
metal-phen complexes that bind to transtition metal ions,
such as Cu2+, Mn2+ and Ag2+ and potentially as antifungal.
Objective: To determine the potential of antifungal effect
and Minimum Inhibitory Concentration (MIC) antifungal
activity of Phenantrolin-1 against resistant strains of
Candida sp with Terbinafine.
Methods: Design of this study is descriptive experimental,
used Microbroth Dilution method. Phenantrolin 1 with a
concentration of 25 |
first_indexed | 2024-03-13T23:21:05Z |
format | Thesis |
id | oai:generic.eprints.org:128474 |
institution | Universiti Gadjah Mada |
last_indexed | 2024-03-13T23:21:05Z |
publishDate | 2014 |
publisher | [Yogyakarta] : Universitas Gadjah Mada |
record_format | dspace |
spelling | oai:generic.eprints.org:1284742016-03-04T08:17:35Z https://repository.ugm.ac.id/128474/ KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1 TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN METODE MICROBROTH DILUTION , WIWID SANTIKO , dr. Titik Nuryastuti,Sp.MK. M.Si, Ph.D. ETD Background: Fungus Infection especially Candida sp isolate, have a high mortality and morbidity in the world and Indonesia. Terbinafine as antifungal known cause resistance. The compound 1,10-Phenantroline has successfully differentiated to Phenantroline-1, which known have antibacterial and antiplasmodial effects. 1- 10,Phenantroline proved and binds to the metal complex form metal-phen complexes that bind to transtition metal ions, such as Cu2+, Mn2+ and Ag2+ and potentially as antifungal. Objective: To determine the potential of antifungal effect and Minimum Inhibitory Concentration (MIC) antifungal activity of Phenantrolin-1 against resistant strains of Candida sp with Terbinafine. Methods: Design of this study is descriptive experimental, used Microbroth Dilution method. Phenantrolin 1 with a concentration of 25 [Yogyakarta] : Universitas Gadjah Mada 2014 Thesis NonPeerReviewed , WIWID SANTIKO and , dr. Titik Nuryastuti,Sp.MK. M.Si, Ph.D. (2014) KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1 TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN METODE MICROBROTH DILUTION. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=68821 |
spellingShingle | ETD , WIWID SANTIKO , dr. Titik Nuryastuti,Sp.MK. M.Si, Ph.D. KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1 TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN METODE MICROBROTH DILUTION |
title | KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1
TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN
METODE MICROBROTH DILUTION |
title_full | KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1
TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN
METODE MICROBROTH DILUTION |
title_fullStr | KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1
TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN
METODE MICROBROTH DILUTION |
title_full_unstemmed | KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1
TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN
METODE MICROBROTH DILUTION |
title_short | KAJIAN POTENSI ANTIFUNGAL SENYAWA FENANTROLIN 1
TERHADAP ISOLAT Candida sp RESISTEN TERBINAFIN DENGAN
METODE MICROBROTH DILUTION |
title_sort | kajian potensi antifungal senyawa fenantrolin 1 terhadap isolat candida sp resisten terbinafin dengan metode microbroth dilution |
topic | ETD |
work_keys_str_mv | AT wiwidsantiko kajianpotensiantifungalsenyawafenantrolin1terhadapisolatcandidaspresistenterbinafindenganmetodemicrobrothdilution AT drtitiknuryastutispmkmsiphd kajianpotensiantifungalsenyawafenantrolin1terhadapisolatcandidaspresistenterbinafindenganmetodemicrobrothdilution |