| Summary: | This research was conducted to study the heart weight, macroscopic, and
histopathologic figure of Sprague-Dawley rat two months after ovariectomy
Eightfemale Sprague-Dawley rats at 2 months of age were randomly
divided into 2groupsof 4. Group A was sham-operated rats (non-ovariectomy) and
group B was ovariectomized was rats. After two months,necropsy was performed
to collect the heart. The heart was weighed and kept in neutral buffered formalin
solution (NBF) 10% for histopathological examination using haematoxylin eosin
staining.
The results showed that the heartweight of ovariectomized rats per 100g
body weight (0.41 ± 0.059 g) was not significantly different (P>0.05) compared to
sham-operated rats (0.46 ± 0.051 g). In macroscopic and histopathological figure
showed that heart and aorta of ovariectomized rats were not showed any changes.
Cardiac muscle cells were still intact in the middle of the nucleus. In the aorta,
there was no atheroma plaque formation. In conclusion, ovariectomy had no effect
on cardiac figure based on macroscopic, histopathological, and heart weight two
months after ovariectomy
Keywords : Heart , ovariectomy
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