| Summary: | Tiroid hormone�s level, such as Thyroxine (T4) and Triiodothyronine (T3)
have a great impact on growth process. It was related against the effect of basal
metabolism elevation rate which had significant role on individual growth and
development. This research was attempted to understanding the comparison
between male and female wistar rat growth rate and its relation with T3-T4 level in
blood serum, and was conducted at Laboratorium Penelitian dan Pengujian
Terpadu (LPPT) UGM Yogyakarta. Fifteen male and female Wistar rats were
used in this research. Those rats had been raised since one month till four months.
Rats were fed of AD2 and RO ad libitum. Rats body weight were measured once a
week and blood samples once a month. Blood samples were collected via the
orbital sinus about 1 ml of blood using mikrohematokrit and placed into a sterile
tube, then centrifuged it 3000 rpm for 15 minutes to make serum. The result
showed that the growth rates of male rats were faster than the female ones. The
male growth rate were 22,8 gram per week and the female rats 12,8 gram per
week. The result using statistic method showed negative correlation between T4
concentrations and growth rate, but positive correlation between T3 concentrations
and growth rate. In conclusion, there are correlations between growth rate and
tiroid hormone�s level in rats (p<0,5)
Key words : Rat Wistar, body weight, thyroxine, triiodothyronine, ELISA
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