PENGARUH PEMBERIAN KUNYIT (Curcuma domestica Val) TERHADAP EKSPRESI VASCULAR ENDOTHELIAL GROWTH FACTOR PADA LUKA INSISI KULIT ANJING (Canine familiaris)
Vascular endothelial growth factor (VEGF) is the important cytokine in angiogenesis during wound healing process. Active substance in turmeric (Curcuma domestica Val) has anti inflammation effect and anti platelet activating factors as platelet aggregation intermediary associated with VEGF expressio...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2014
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| author | , NIKE WINDIARTI , drh. Agus Budi Santosa., MS. |
| author_facet | , NIKE WINDIARTI , drh. Agus Budi Santosa., MS. |
| author_sort | , NIKE WINDIARTI |
| collection | UGM |
| description | Vascular endothelial growth factor (VEGF) is the important cytokine in
angiogenesis during wound healing process. Active substance in turmeric
(Curcuma domestica Val) has anti inflammation effect and anti platelet activating
factors as platelet aggregation intermediary associated with VEGF expression on
wound. This research aimed to identify effect of turmeric (Curcuma domestica
Val) on vascular endothelial growth factor expression on dog (Canine familiaris)
skin incision wound.
The right and left side of dog�s flank is made up of three wounds incision
until fascia layer with the length of wound incision is 6 cm. Distance between
wound is 3 cm then wound sewn with cotton threads and given treatment namely
control, fresh turmeric and turmeric powder. The application of turmeric is done
twice in a day for one week. On the 3rd and 6th day, the skin tissue on wound is
taken than made histology preparation for painting of imunohistokimia VEGF by
used rabbit polyclonal antibody. Data taken by counting the inflammation cell that
express VEGF protein which is brown color on membrane and cytoplasm cell by
using microscope with 400 times magnification on five fields of view. The data
analyzed use One Way ANOVA method continued by Tukey test.
The result showed that giving turmeric (Curcuma domestica Val) effect on
the expression of VEGF in incision wound of dog�s skin (P < 0,05). The effect
characterized by the average decrease of inflammation cell that express VEGF.
On the 3rd day, the inflammation cells that express VEGF on fresh turmeric and
turmeric powder lower than control. On the 6th day, the inflammation cell on fresh
turmeric and turmeric powder is assumed to be lower than control. |
| first_indexed | 2024-03-13T23:30:24Z |
| format | Thesis |
| id | oai:generic.eprints.org:130762 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T23:30:24Z |
| publishDate | 2014 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1307622016-03-04T08:03:22Z https://repository.ugm.ac.id/130762/ PENGARUH PEMBERIAN KUNYIT (Curcuma domestica Val) TERHADAP EKSPRESI VASCULAR ENDOTHELIAL GROWTH FACTOR PADA LUKA INSISI KULIT ANJING (Canine familiaris) , NIKE WINDIARTI , drh. Agus Budi Santosa., MS. ETD Vascular endothelial growth factor (VEGF) is the important cytokine in angiogenesis during wound healing process. Active substance in turmeric (Curcuma domestica Val) has anti inflammation effect and anti platelet activating factors as platelet aggregation intermediary associated with VEGF expression on wound. This research aimed to identify effect of turmeric (Curcuma domestica Val) on vascular endothelial growth factor expression on dog (Canine familiaris) skin incision wound. The right and left side of dog�s flank is made up of three wounds incision until fascia layer with the length of wound incision is 6 cm. Distance between wound is 3 cm then wound sewn with cotton threads and given treatment namely control, fresh turmeric and turmeric powder. The application of turmeric is done twice in a day for one week. On the 3rd and 6th day, the skin tissue on wound is taken than made histology preparation for painting of imunohistokimia VEGF by used rabbit polyclonal antibody. Data taken by counting the inflammation cell that express VEGF protein which is brown color on membrane and cytoplasm cell by using microscope with 400 times magnification on five fields of view. The data analyzed use One Way ANOVA method continued by Tukey test. The result showed that giving turmeric (Curcuma domestica Val) effect on the expression of VEGF in incision wound of dog�s skin (P < 0,05). The effect characterized by the average decrease of inflammation cell that express VEGF. On the 3rd day, the inflammation cells that express VEGF on fresh turmeric and turmeric powder lower than control. On the 6th day, the inflammation cell on fresh turmeric and turmeric powder is assumed to be lower than control. [Yogyakarta] : Universitas Gadjah Mada 2014 Thesis NonPeerReviewed , NIKE WINDIARTI and , drh. Agus Budi Santosa., MS. (2014) PENGARUH PEMBERIAN KUNYIT (Curcuma domestica Val) TERHADAP EKSPRESI VASCULAR ENDOTHELIAL GROWTH FACTOR PADA LUKA INSISI KULIT ANJING (Canine familiaris). UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=71191 |
| spellingShingle | ETD , NIKE WINDIARTI , drh. Agus Budi Santosa., MS. PENGARUH PEMBERIAN KUNYIT (Curcuma domestica Val) TERHADAP EKSPRESI VASCULAR ENDOTHELIAL GROWTH FACTOR PADA LUKA INSISI KULIT ANJING (Canine familiaris) |
| title | PENGARUH PEMBERIAN KUNYIT (Curcuma domestica Val) TERHADAP EKSPRESI VASCULAR ENDOTHELIAL
GROWTH FACTOR PADA LUKA INSISI KULIT ANJING (Canine familiaris) |
| title_full | PENGARUH PEMBERIAN KUNYIT (Curcuma domestica Val) TERHADAP EKSPRESI VASCULAR ENDOTHELIAL
GROWTH FACTOR PADA LUKA INSISI KULIT ANJING (Canine familiaris) |
| title_fullStr | PENGARUH PEMBERIAN KUNYIT (Curcuma domestica Val) TERHADAP EKSPRESI VASCULAR ENDOTHELIAL
GROWTH FACTOR PADA LUKA INSISI KULIT ANJING (Canine familiaris) |
| title_full_unstemmed | PENGARUH PEMBERIAN KUNYIT (Curcuma domestica Val) TERHADAP EKSPRESI VASCULAR ENDOTHELIAL
GROWTH FACTOR PADA LUKA INSISI KULIT ANJING (Canine familiaris) |
| title_short | PENGARUH PEMBERIAN KUNYIT (Curcuma domestica Val) TERHADAP EKSPRESI VASCULAR ENDOTHELIAL
GROWTH FACTOR PADA LUKA INSISI KULIT ANJING (Canine familiaris) |
| title_sort | pengaruh pemberian kunyit curcuma domestica val terhadap ekspresi vascular endothelial growth factor pada luka insisi kulit anjing canine familiaris |
| topic | ETD |
| work_keys_str_mv | AT nikewindiarti pengaruhpemberiankunyitcurcumadomesticavalterhadapekspresivascularendothelialgrowthfactorpadalukainsisikulitanjingcaninefamiliaris AT drhagusbudisantosams pengaruhpemberiankunyitcurcumadomesticavalterhadapekspresivascularendothelialgrowthfactorpadalukainsisikulitanjingcaninefamiliaris |