PENGARUH EKSTRAK METHANOL TUMBUHAN Hoodia macrantha SEBAGAI PENEKAN NAFSU MAKAN TERHADAP MEMORI SPASIAL MENCIT JANTAN
Background : Hoodia macrantha is plants that are found in Kalahari South Africa. This plant commonly used by local residents as appetite suppressor. Recent research has found a substance called P57 and it is believed that responsible in suppressing appetite. Nowadays, there are many companies produc...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2014
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| _version_ | 1826048502709354496 |
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| author | , RIFKI BACHTIAR , Prof. DR. Mae Sri Hartati W, M.Si, Apt. |
| author_facet | , RIFKI BACHTIAR , Prof. DR. Mae Sri Hartati W, M.Si, Apt. |
| author_sort | , RIFKI BACHTIAR |
| collection | UGM |
| description | Background : Hoodia macrantha is plants that are found
in Kalahari South Africa. This plant commonly used by
local residents as appetite suppressor. Recent research
has found a substance called P57 and it is believed
that responsible in suppressing appetite. Nowadays,
there are many companies producing substances to be
marketed without further research. Weight problems have
been a universal problem and consumption of slimming
drugs become a routine for people without knowing
effects. This research will examine the influence of
Hoodia macrantha methanol extract to spatial memory
arrangement of male mice.
Objective : The purpose of this research is to know the
influence of Hoodia macrantha methanol extract to
memory special arrangement of male mice with oral
route.
Methods : Hoodia macrantha plant was 12 months old and
extracted using methanol. The making of the suspension
using a dose of 0, 5, 15, and 50 mg/kgBB/hari/1mL. Mice
were divided into 4 groups according to the dose.
Extract administered once a day for 7 days. 24 hours
after the administration spatial memory was measured
using Morris water maze with 3 trial for 3 days and
sensorymotor observations on the third day. The data
obtained from the observations were analyzed using oneway
ANOVA. If p> 0.05 then the result is significant, p
<0.05, it is not significant.
Results : The results of the comparison between groups.
In trial 1 obtained p = 0.891, p = 0.958 trial 2, trial
3 p = 0.465, and trial 4 (sensorimotor) p = 0.781.
There were no significant results (p> 0.05).
Conclusion : Methanol extract of Hoodia macrantha with
doses of 5, 15, and 50 mg/kgBB/hari/1mL, does not
affect spatial memory of male mice. |
| first_indexed | 2024-03-13T23:30:39Z |
| format | Thesis |
| id | oai:generic.eprints.org:130842 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T23:30:39Z |
| publishDate | 2014 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1308422016-03-04T08:09:26Z https://repository.ugm.ac.id/130842/ PENGARUH EKSTRAK METHANOL TUMBUHAN Hoodia macrantha SEBAGAI PENEKAN NAFSU MAKAN TERHADAP MEMORI SPASIAL MENCIT JANTAN , RIFKI BACHTIAR , Prof. DR. Mae Sri Hartati W, M.Si, Apt. ETD Background : Hoodia macrantha is plants that are found in Kalahari South Africa. This plant commonly used by local residents as appetite suppressor. Recent research has found a substance called P57 and it is believed that responsible in suppressing appetite. Nowadays, there are many companies producing substances to be marketed without further research. Weight problems have been a universal problem and consumption of slimming drugs become a routine for people without knowing effects. This research will examine the influence of Hoodia macrantha methanol extract to spatial memory arrangement of male mice. Objective : The purpose of this research is to know the influence of Hoodia macrantha methanol extract to memory special arrangement of male mice with oral route. Methods : Hoodia macrantha plant was 12 months old and extracted using methanol. The making of the suspension using a dose of 0, 5, 15, and 50 mg/kgBB/hari/1mL. Mice were divided into 4 groups according to the dose. Extract administered once a day for 7 days. 24 hours after the administration spatial memory was measured using Morris water maze with 3 trial for 3 days and sensorymotor observations on the third day. The data obtained from the observations were analyzed using oneway ANOVA. If p> 0.05 then the result is significant, p <0.05, it is not significant. Results : The results of the comparison between groups. In trial 1 obtained p = 0.891, p = 0.958 trial 2, trial 3 p = 0.465, and trial 4 (sensorimotor) p = 0.781. There were no significant results (p> 0.05). Conclusion : Methanol extract of Hoodia macrantha with doses of 5, 15, and 50 mg/kgBB/hari/1mL, does not affect spatial memory of male mice. [Yogyakarta] : Universitas Gadjah Mada 2014 Thesis NonPeerReviewed , RIFKI BACHTIAR and , Prof. DR. Mae Sri Hartati W, M.Si, Apt. (2014) PENGARUH EKSTRAK METHANOL TUMBUHAN Hoodia macrantha SEBAGAI PENEKAN NAFSU MAKAN TERHADAP MEMORI SPASIAL MENCIT JANTAN. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=71275 |
| spellingShingle | ETD , RIFKI BACHTIAR , Prof. DR. Mae Sri Hartati W, M.Si, Apt. PENGARUH EKSTRAK METHANOL TUMBUHAN Hoodia macrantha SEBAGAI PENEKAN NAFSU MAKAN TERHADAP MEMORI SPASIAL MENCIT JANTAN |
| title | PENGARUH EKSTRAK METHANOL TUMBUHAN Hoodia macrantha SEBAGAI PENEKAN NAFSU MAKAN TERHADAP MEMORI SPASIAL MENCIT JANTAN |
| title_full | PENGARUH EKSTRAK METHANOL TUMBUHAN Hoodia macrantha SEBAGAI PENEKAN NAFSU MAKAN TERHADAP MEMORI SPASIAL MENCIT JANTAN |
| title_fullStr | PENGARUH EKSTRAK METHANOL TUMBUHAN Hoodia macrantha SEBAGAI PENEKAN NAFSU MAKAN TERHADAP MEMORI SPASIAL MENCIT JANTAN |
| title_full_unstemmed | PENGARUH EKSTRAK METHANOL TUMBUHAN Hoodia macrantha SEBAGAI PENEKAN NAFSU MAKAN TERHADAP MEMORI SPASIAL MENCIT JANTAN |
| title_short | PENGARUH EKSTRAK METHANOL TUMBUHAN Hoodia macrantha SEBAGAI PENEKAN NAFSU MAKAN TERHADAP MEMORI SPASIAL MENCIT JANTAN |
| title_sort | pengaruh ekstrak methanol tumbuhan hoodia macrantha sebagai penekan nafsu makan terhadap memori spasial mencit jantan |
| topic | ETD |
| work_keys_str_mv | AT rifkibachtiar pengaruhekstrakmethanoltumbuhanhoodiamacranthasebagaipenekannafsumakanterhadapmemorispasialmencitjantan AT profdrmaesrihartatiwmsiapt pengaruhekstrakmethanoltumbuhanhoodiamacranthasebagaipenekannafsumakanterhadapmemorispasialmencitjantan |