BIOAKTIVITAS N,O-KARBOKSIMETIL KITOSAN TERHADAP BAKTERI PATOGEN PADA IKAN BUDIDAYA
Chitosan has been known as an antibacterial agent which is biodegradable, biocompatible, but insoluble in neutral solvents. Modification into N,O-carboxymethyl chitosan (N,O-CMC) was done in order to increase solubility in neutral solvent without changing its bioactivity so application as an antibac...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2014
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| _version_ | 1797035720071708672 |
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| author | , HENDRI SETIAWAN , Dr. Ir. Triyanto, M.Si. |
| author_facet | , HENDRI SETIAWAN , Dr. Ir. Triyanto, M.Si. |
| author_sort | , HENDRI SETIAWAN |
| collection | UGM |
| description | Chitosan has been known as an antibacterial agent which is biodegradable, biocompatible, but
insoluble in neutral solvents. Modification into N,O-carboxymethyl chitosan (N,O-CMC) was
done in order to increase solubility in neutral solvent without changing its bioactivity so
application as an antibacterial agent against fish disease bacteria is allowed. Three methods
were employed to produce N,O-CMC. Characterization was done in order to know the
important characteristics of chitosan and its derivate, i.e. yield, solubility, chemical bond and
degree of deacetylation. The result in characterization showed increasing in solubility and
degree of deacetylation. The three products were tested against fish pathogens Aeromonas
hydrophila, Streptococcus sp. and Vibrio spp. Two types of N,O-CMC products have
antibacterial activity against Streptococcus sp., and Vibrio spp. None of N,O-CMC products
showed antibacterial activity against Aeromonas hydrophila. The best concentration of Liu�s
N,O-CMC and Hayes�s N,O-CMC against bacteria in this experiment is 20 mg/mL.
Keywords : antibacterial activity, chitosan, N,O-carboxymethyl chitosan, fish disease bacteria,
MIC. |
| first_indexed | 2024-03-13T23:35:09Z |
| format | Thesis |
| id | oai:generic.eprints.org:132101 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T23:35:09Z |
| publishDate | 2014 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1321012016-03-04T07:56:52Z https://repository.ugm.ac.id/132101/ BIOAKTIVITAS N,O-KARBOKSIMETIL KITOSAN TERHADAP BAKTERI PATOGEN PADA IKAN BUDIDAYA , HENDRI SETIAWAN , Dr. Ir. Triyanto, M.Si. ETD Chitosan has been known as an antibacterial agent which is biodegradable, biocompatible, but insoluble in neutral solvents. Modification into N,O-carboxymethyl chitosan (N,O-CMC) was done in order to increase solubility in neutral solvent without changing its bioactivity so application as an antibacterial agent against fish disease bacteria is allowed. Three methods were employed to produce N,O-CMC. Characterization was done in order to know the important characteristics of chitosan and its derivate, i.e. yield, solubility, chemical bond and degree of deacetylation. The result in characterization showed increasing in solubility and degree of deacetylation. The three products were tested against fish pathogens Aeromonas hydrophila, Streptococcus sp. and Vibrio spp. Two types of N,O-CMC products have antibacterial activity against Streptococcus sp., and Vibrio spp. None of N,O-CMC products showed antibacterial activity against Aeromonas hydrophila. The best concentration of Liu�s N,O-CMC and Hayes�s N,O-CMC against bacteria in this experiment is 20 mg/mL. Keywords : antibacterial activity, chitosan, N,O-carboxymethyl chitosan, fish disease bacteria, MIC. [Yogyakarta] : Universitas Gadjah Mada 2014 Thesis NonPeerReviewed , HENDRI SETIAWAN and , Dr. Ir. Triyanto, M.Si. (2014) BIOAKTIVITAS N,O-KARBOKSIMETIL KITOSAN TERHADAP BAKTERI PATOGEN PADA IKAN BUDIDAYA. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=72617 |
| spellingShingle | ETD , HENDRI SETIAWAN , Dr. Ir. Triyanto, M.Si. BIOAKTIVITAS N,O-KARBOKSIMETIL KITOSAN TERHADAP BAKTERI PATOGEN PADA IKAN BUDIDAYA |
| title | BIOAKTIVITAS N,O-KARBOKSIMETIL KITOSAN TERHADAP BAKTERI PATOGEN PADA IKAN BUDIDAYA |
| title_full | BIOAKTIVITAS N,O-KARBOKSIMETIL KITOSAN TERHADAP BAKTERI PATOGEN PADA IKAN BUDIDAYA |
| title_fullStr | BIOAKTIVITAS N,O-KARBOKSIMETIL KITOSAN TERHADAP BAKTERI PATOGEN PADA IKAN BUDIDAYA |
| title_full_unstemmed | BIOAKTIVITAS N,O-KARBOKSIMETIL KITOSAN TERHADAP BAKTERI PATOGEN PADA IKAN BUDIDAYA |
| title_short | BIOAKTIVITAS N,O-KARBOKSIMETIL KITOSAN TERHADAP BAKTERI PATOGEN PADA IKAN BUDIDAYA |
| title_sort | bioaktivitas n o karboksimetil kitosan terhadap bakteri patogen pada ikan budidaya |
| topic | ETD |
| work_keys_str_mv | AT hendrisetiawan bioaktivitasnokarboksimetilkitosanterhadapbakteripatogenpadaikanbudidaya AT drirtriyantomsi bioaktivitasnokarboksimetilkitosanterhadapbakteripatogenpadaikanbudidaya |