PROFIL LIPID DAN GLUKOSA SERUM PADA TIKUS SPRAGUE-DAWLEY YANG DIBERI PAKAN TEPUNG KORO PEDANG (Canavalia ensiformis) PUTIH

Jackbean are legumes, that extensively cultivated in Indonesia. Currently jackbean started being develop to create innovative food products. However, it is not certain this jackbean consumption effects on health, especially in serum lipid profile (triglycerides, total cholesterol, HDL cholesterol, L...

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Bibliographic Details
Main Authors: , DEA BUDIELFREDA, , Prof. Dr. Ir. Agnes Murdiati, MS.
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2014
Subjects:
ETD
Description
Summary:Jackbean are legumes, that extensively cultivated in Indonesia. Currently jackbean started being develop to create innovative food products. However, it is not certain this jackbean consumption effects on health, especially in serum lipid profile (triglycerides, total cholesterol, HDL cholesterol, LDL cholesterol), blood glucose, liver and kidney tissue profile. This study is a kind of experimental research with a completely randomized design. This study used 18 male Sprague-Dawley rats divided into three groups, one group fed a standard AIN 93-G, one group fed raw jackbean flour, and one group fed jackbean flour that have been soaked and blanching. Feeding interventions conducted over 28 days. At the beginning and end of the intervention period, there were blood sampling to test levels of triglycerides, total cholesterol, HDL cholesterol, LDL cholesterol, and glucose. At the end of the experiment, the liver and kidney of rats were taken. The liver and kidney tissue was made to be preparats and coloured by hematoxylin-eosin (HE). The preparats were observed in the microscope and determined whether it has characteristics that were different from normal tissue. Jackbean flour feeding for 28 days causes, levels of triglycerides, total cholesterol, LDL cholesterol, and glucose in rats are lower than those fed the standard AIN 93-G, whereas for HDL cholesterol levels higher than those fed the standard AIN 93 -G . The liver and kidney tissue of rats that consumed jackbean have no different than that consumed the standard feed, liver and kidney in normal circumstances.