Profil Serum Amyloid A (SAA) pada Pasien Angina Pektoris Stabil di RSUP DR. Sardjito Yogyakarta
Background : Stable Angina Pectoris is a symptom that occur because of myocardial ischemia that caused by fat deposition on the wall of coronarian artery (atherosclerosis), when the progress still remains it can lead to myocardial infarction and furthermore death. Serum Amyloid A is one of the clini...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2014
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| Summary: | Background : Stable Angina Pectoris is a symptom
that occur because of myocardial ischemia that caused
by fat deposition on the wall of coronarian artery
(atherosclerosis), when the progress still remains it
can lead to myocardial infarction and furthermore
death. Serum Amyloid A is one of the clinical chemical
parameter as a sign of acute inflamation, that
suspected play an important role on progression of
atherosclerosis. In general, function of SAA as an
specific laboratory marker can�t be precisely
postulated, there are some things that remains unclear
according to researches that contradictively one to
another.
Methods : The study design was a analytical
descriptive study of patients with stable angina
pectoris that received treatment in ICCU Hospital Dr .
Sardjito . Examination of SAA was measured by sandwich
ELISA method.
Results : There were 26 patients with stable angina
pectoris that joined this research. Analysis with Mann
Whitney test come out with a result which says that
there is no significant difference of SAA level between
patient with risk factor of atherosclerosis and without
risk factor. There is no significant correlation
between SAA and other clinical chemical parameter that
analyzed by Spearman test.
Conclusions : There is a significant diference of SAA
level on patient with diaberes as a risk factor of
atherosclerosis. There is no significant correlation
between SAA and other clinical chemical parameter. |
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