Pengaruh polimorfisme C677T gena methylentetrahydrofolate reductase (MTHFR) terhadap kejadian relaps pada anak dengan Leukemia limfoblastik akut (LLA)
Methotrexate is a key drug in acute lymphoblastic leukemia (ALL) treatment. It inhibits DNA replication by blocking the conversion of 5,10 methylenetetrahydrofolate to 5-methylenetetrahydrofolate by methylene tetrahydrofolate reductase, a critical enzyme involved in folate metabolism, DNA methylatio...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2014
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