EFEKTIFITAS EKSTRAK PEGAGAN 750 mg dan 1000 mg DIBANDING ASAM FOLAT 3 mg TERHADAP PERBAIKAN SKOR MONTREAL COGNITIF ASSESMENT (MoCA-Ina) PASIEN GANGGUAN KOGNITIF PASCASTROKE INFARK
Stroke can cause cognitive decline known as cognitive vascular impairment (VCI) and incidence of cognitive impairment after stroke is about 20-30% and can develope to demensia. Therapy for VCI has to include management of risk factor and specific treatment for the VCI itself. One of herbs that can b...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2014
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| _version_ | 1826049103886286848 |
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| author | , Kun Marisa Farhana , Prof. Dr.dr. Samekto Wibowo, P.FarK,SpFK(K),Sp.S(K) |
| author_facet | , Kun Marisa Farhana , Prof. Dr.dr. Samekto Wibowo, P.FarK,SpFK(K),Sp.S(K) |
| author_sort | , Kun Marisa Farhana |
| collection | UGM |
| description | Stroke can cause cognitive decline known as cognitive vascular impairment (VCI) and
incidence of cognitive impairment after stroke is about 20-30% and can develope to demensia.
Therapy for VCI has to include management of risk factor and specific treatment for the VCI itself.
One of herbs that can be used for treatment cognitive impairment is Pegagan (centella asiatica), but
most of the study still held in preclinic setting.
This study conduct with quasi experimental design. Subject of the study is VCI patient who
treated outpatient in RSUP Dr. Sardjito and RSUD Wates policlinic. Subjects were devided into 3
groups, which is treated by Pegagan ekstract 750 mg/day, pegagan ekstract 1000 mg/day, and folic
acid 3 mg/day within 6 weeks. Assesment of VCI is used Montreal Cognitive Assesment Indonesian
version, which is score below 26 is diagnosed as VCI. Statistical analysis by chi-square test for
categorical variable and one-way ANOVA for numerical variable.
48 subjects participated this study,17 were treated by pegagan 750 mg/day, 17 were treated by
pegagan 1000 mg/day and 14 were treated by folic acid 3 mg/day. Pair t-test analysis shows that
subjects treated with pegagan 750 mg, 1000 mg, and folic acid 3 mg perhari selama 6 minggu is
efective to improve VCI showed by addition of MoCA-Ina score at the end of study compared by
baseline. Mean � MoCA-Ina score after6 weeks treatment in Pegagan 1000 mg subjects is 5,53±3,52
(p<0,001 |
| first_indexed | 2024-03-13T23:40:41Z |
| format | Thesis |
| id | oai:generic.eprints.org:133843 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T23:40:41Z |
| publishDate | 2014 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1338432016-03-04T07:58:09Z https://repository.ugm.ac.id/133843/ EFEKTIFITAS EKSTRAK PEGAGAN 750 mg dan 1000 mg DIBANDING ASAM FOLAT 3 mg TERHADAP PERBAIKAN SKOR MONTREAL COGNITIF ASSESMENT (MoCA-Ina) PASIEN GANGGUAN KOGNITIF PASCASTROKE INFARK , Kun Marisa Farhana , Prof. Dr.dr. Samekto Wibowo, P.FarK,SpFK(K),Sp.S(K) ETD Stroke can cause cognitive decline known as cognitive vascular impairment (VCI) and incidence of cognitive impairment after stroke is about 20-30% and can develope to demensia. Therapy for VCI has to include management of risk factor and specific treatment for the VCI itself. One of herbs that can be used for treatment cognitive impairment is Pegagan (centella asiatica), but most of the study still held in preclinic setting. This study conduct with quasi experimental design. Subject of the study is VCI patient who treated outpatient in RSUP Dr. Sardjito and RSUD Wates policlinic. Subjects were devided into 3 groups, which is treated by Pegagan ekstract 750 mg/day, pegagan ekstract 1000 mg/day, and folic acid 3 mg/day within 6 weeks. Assesment of VCI is used Montreal Cognitive Assesment Indonesian version, which is score below 26 is diagnosed as VCI. Statistical analysis by chi-square test for categorical variable and one-way ANOVA for numerical variable. 48 subjects participated this study,17 were treated by pegagan 750 mg/day, 17 were treated by pegagan 1000 mg/day and 14 were treated by folic acid 3 mg/day. Pair t-test analysis shows that subjects treated with pegagan 750 mg, 1000 mg, and folic acid 3 mg perhari selama 6 minggu is efective to improve VCI showed by addition of MoCA-Ina score at the end of study compared by baseline. Mean � MoCA-Ina score after6 weeks treatment in Pegagan 1000 mg subjects is 5,53±3,52 (p<0,001 [Yogyakarta] : Universitas Gadjah Mada 2014 Thesis NonPeerReviewed , Kun Marisa Farhana and , Prof. Dr.dr. Samekto Wibowo, P.FarK,SpFK(K),Sp.S(K) (2014) EFEKTIFITAS EKSTRAK PEGAGAN 750 mg dan 1000 mg DIBANDING ASAM FOLAT 3 mg TERHADAP PERBAIKAN SKOR MONTREAL COGNITIF ASSESMENT (MoCA-Ina) PASIEN GANGGUAN KOGNITIF PASCASTROKE INFARK. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=74703 |
| spellingShingle | ETD , Kun Marisa Farhana , Prof. Dr.dr. Samekto Wibowo, P.FarK,SpFK(K),Sp.S(K) EFEKTIFITAS EKSTRAK PEGAGAN 750 mg dan 1000 mg DIBANDING ASAM FOLAT 3 mg TERHADAP PERBAIKAN SKOR MONTREAL COGNITIF ASSESMENT (MoCA-Ina) PASIEN GANGGUAN KOGNITIF PASCASTROKE INFARK |
| title | EFEKTIFITAS EKSTRAK PEGAGAN 750 mg dan 1000 mg DIBANDING ASAM FOLAT 3 mg TERHADAP PERBAIKAN SKOR MONTREAL COGNITIF ASSESMENT (MoCA-Ina) PASIEN GANGGUAN KOGNITIF PASCASTROKE INFARK |
| title_full | EFEKTIFITAS EKSTRAK PEGAGAN 750 mg dan 1000 mg DIBANDING ASAM FOLAT 3 mg TERHADAP PERBAIKAN SKOR MONTREAL COGNITIF ASSESMENT (MoCA-Ina) PASIEN GANGGUAN KOGNITIF PASCASTROKE INFARK |
| title_fullStr | EFEKTIFITAS EKSTRAK PEGAGAN 750 mg dan 1000 mg DIBANDING ASAM FOLAT 3 mg TERHADAP PERBAIKAN SKOR MONTREAL COGNITIF ASSESMENT (MoCA-Ina) PASIEN GANGGUAN KOGNITIF PASCASTROKE INFARK |
| title_full_unstemmed | EFEKTIFITAS EKSTRAK PEGAGAN 750 mg dan 1000 mg DIBANDING ASAM FOLAT 3 mg TERHADAP PERBAIKAN SKOR MONTREAL COGNITIF ASSESMENT (MoCA-Ina) PASIEN GANGGUAN KOGNITIF PASCASTROKE INFARK |
| title_short | EFEKTIFITAS EKSTRAK PEGAGAN 750 mg dan 1000 mg DIBANDING ASAM FOLAT 3 mg TERHADAP PERBAIKAN SKOR MONTREAL COGNITIF ASSESMENT (MoCA-Ina) PASIEN GANGGUAN KOGNITIF PASCASTROKE INFARK |
| title_sort | efektifitas ekstrak pegagan 750 mg dan 1000 mg dibanding asam folat 3 mg terhadap perbaikan skor montreal cognitif assesment moca ina pasien gangguan kognitif pascastroke infark |
| topic | ETD |
| work_keys_str_mv | AT kunmarisafarhana efektifitasekstrakpegagan750mgdan1000mgdibandingasamfolat3mgterhadapperbaikanskormontrealcognitifassesmentmocainapasiengangguankognitifpascastrokeinfark AT profdrdrsamektowibowopfarkspfkkspsk efektifitasekstrakpegagan750mgdan1000mgdibandingasamfolat3mgterhadapperbaikanskormontrealcognitifassesmentmocainapasiengangguankognitifpascastrokeinfark |