| Summary: | Depression is an independent predictor of cardiovascular events. Increased platelet reactivity is one of several possible mechanisms proposed to explain the relationship between psychosocial factors with coronary heart disease. Mean platelet volume (MPV) is an indicator of platelet activation. MPV associated with
major cardiovascular events in coronary heart disease.
This study aimed to determine the correlation of MPV with depression symptoms in patients with stable angina pectoris.The study design was cross-sectional study. Sampling was carried out in sequence from Stable Angina Pectoris patients who were treated at internal medicine department of Dr. Sardjito hospital yogyakarta. MPV and HAD score were measured once on admission. Data presented as a descriptive analysis of the subjects characteristics in average and standard deviation. Correlation of MPV with depression symptoms in patient with Stable Angina Pectoris assessed with Pearson's correlation. The results were considered at the significance level of p<0.05.
There were 40 subjects, consisting of 20 Stable Angina Pectoris with depression and 20 Stable Angina Pectoris without depression. The mean levels of MPV in this study was 7,56 ± 0,95 fl, mean MPV in SAP patients with depression was 8,45 ± 0,82 fl, whereas in Stable Angina Pectoris patients without depression was 7,68 ± 0,99 fl.
There is difference level of MPV in Stable Angina Pectoris patients with depression and without depression p = 0.009.
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