KADAR GLUKOSA RENDAH CAIRAN SEREBROSPINAL SEBAGAI PREDIKTOR KEMATIAN MENINGITIS BAKTERIAL PADA ANAK

Bacterial meningitis causes morbidity and mortality in children. Some researches had been done in order to find the predictors of mortality of bacterial meningitis in children. Low cerebrospinal (CSF) glucose level was hypothesized as the pathological process happened in brain. This study is aimed t...

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Bibliographic Details
Main Authors: , ERIKA PRIMADIANTI HASANAH, , dr. Sekar Satiti, Sp.S(K).
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2014
Subjects:
ETD
Description
Summary:Bacterial meningitis causes morbidity and mortality in children. Some researches had been done in order to find the predictors of mortality of bacterial meningitis in children. Low cerebrospinal (CSF) glucose level was hypothesized as the pathological process happened in brain. This study is aimed to know whether a low CSF glucose level is a mortality predictor of bacterial meningitis in children or not. The design of this study was retrospective cohort study by collecting data from medical records. Subjects of the study are children who were diagnosed as bacterial meningitis, that categorized as low CSF glucose leve�l 4(0 mg/dl) and normal/high CSF glucose level (>40mg/dl), each group with 34 patients. Then we followed whether there was death or not as patients outcome. Subjects consists of 44 boys and 24 girls. Most of them was 1-12 months old (40 patients). Fifteen patients died (22,1%) and 53 patients still alive (77,9%). Based on the bivariat analysis, we revealed hat sex (girl), shock, and hyponatremia (<130 mEq/l) were associated with mortality and statistically significant. Based on multivariate analysis, sex (girl), shock and hyponatremia were the independent variabels of mortality predictor. Low CSF glucose level proved as a mortality predictor (RR 3,209