Evaluation of anti-hypertensive drug utilisation and cost in Hospital Tengku Ampuan Afzan, Kuantan
Introduction: Hypertension is one of the most important risk factors for cardiovascular disease in Malaysia. The prevalence of hypertension nearly doubled over a ten-year period (1986 – 1996). This has resulted in a significant rise in its attendant cost. We aim to review the institutional anti-hype...
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| Format: | Article |
| Language: | English |
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Faculty of Medicine, International Islamic University Malaysia
2009
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| Online Access: | http://irep.iium.edu.my/1350/1/Evaluation_of_anti-hypertensive_drug_utilisation_and_cost_in_Hospital_Tengku_Ampuan_Afzan%2C_Kuantan.pdf |
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| author | Mohd Shah, Azarisman Shah Abdullah, Aszrin Mohamed, Sahimi Abdullah Ngow, Harris Omar, Ahmad Marzuki Ab Rahman, Jamalludin Satwi, Sapari Oteh, Maskon |
| author_facet | Mohd Shah, Azarisman Shah Abdullah, Aszrin Mohamed, Sahimi Abdullah Ngow, Harris Omar, Ahmad Marzuki Ab Rahman, Jamalludin Satwi, Sapari Oteh, Maskon |
| author_sort | Mohd Shah, Azarisman Shah |
| collection | IIUM |
| description | Introduction: Hypertension is one of the most important risk factors for cardiovascular disease in Malaysia. The prevalence of hypertension nearly doubled over a ten-year period (1986 – 1996). This has resulted in a significant rise in its attendant cost. We aim to review the institutional anti-hypertensive use, the cost incurred and the implications on management in our local setting. Materials and Methods: A retrospective review of the annual cost (2006) of anti-hypertensive medications was undertaken at the Department of Pharmacy, Hospital Tengku Ampuan Afzan, a 600-bed major regional hospital on the east-coast of Malaysia. The total number of prescriptions given out and the total cost per drug is then factored to give the annual cost per drug per person in a percentage of the total annual expenditure. Results: The majority of patients were on either 2 (46.5%) or 3 (25.9%) anti-hypertensives. The most frequently prescribed medications were ACE Inhibitors (33.45%), Calcium channel blockers (29.63%), diuretics (16.67%) and β-blockers (13.64%). In terms of cost however, the Calcium channel blockers constituted the greatest percentage of the annual anti-hypertensive budget (63.67%) compared to ACE Inhibitors at just 20.04% of the annual expenditure. The least costly group of drugs is the diuretic making up 16.67% of the total annual prescriptions but only constituting 1.23% of the annual cost. Conclusion: The majority of patients were on ACE Inhibitors and/or Calcium channel blockers. This has huge monetary implications as they represent a large proportion of the annual antihypertensive allocation. There may be a need to reverse the trend in the developing world due to cost restrictions. |
| first_indexed | 2024-03-05T22:29:09Z |
| format | Article |
| id | oai:generic.eprints.org:1350 |
| institution | International Islamic University Malaysia |
| language | English |
| last_indexed | 2024-03-05T22:29:09Z |
| publishDate | 2009 |
| publisher | Faculty of Medicine, International Islamic University Malaysia |
| record_format | dspace |
| spelling | oai:generic.eprints.org:13502016-03-10T03:59:03Z http://irep.iium.edu.my/1350/ Evaluation of anti-hypertensive drug utilisation and cost in Hospital Tengku Ampuan Afzan, Kuantan Mohd Shah, Azarisman Shah Abdullah, Aszrin Mohamed, Sahimi Abdullah Ngow, Harris Omar, Ahmad Marzuki Ab Rahman, Jamalludin Satwi, Sapari Oteh, Maskon R Medicine (General) Introduction: Hypertension is one of the most important risk factors for cardiovascular disease in Malaysia. The prevalence of hypertension nearly doubled over a ten-year period (1986 – 1996). This has resulted in a significant rise in its attendant cost. We aim to review the institutional anti-hypertensive use, the cost incurred and the implications on management in our local setting. Materials and Methods: A retrospective review of the annual cost (2006) of anti-hypertensive medications was undertaken at the Department of Pharmacy, Hospital Tengku Ampuan Afzan, a 600-bed major regional hospital on the east-coast of Malaysia. The total number of prescriptions given out and the total cost per drug is then factored to give the annual cost per drug per person in a percentage of the total annual expenditure. Results: The majority of patients were on either 2 (46.5%) or 3 (25.9%) anti-hypertensives. The most frequently prescribed medications were ACE Inhibitors (33.45%), Calcium channel blockers (29.63%), diuretics (16.67%) and β-blockers (13.64%). In terms of cost however, the Calcium channel blockers constituted the greatest percentage of the annual anti-hypertensive budget (63.67%) compared to ACE Inhibitors at just 20.04% of the annual expenditure. The least costly group of drugs is the diuretic making up 16.67% of the total annual prescriptions but only constituting 1.23% of the annual cost. Conclusion: The majority of patients were on ACE Inhibitors and/or Calcium channel blockers. This has huge monetary implications as they represent a large proportion of the annual antihypertensive allocation. There may be a need to reverse the trend in the developing world due to cost restrictions. Faculty of Medicine, International Islamic University Malaysia 2009-12 Article PeerReviewed application/pdf en http://irep.iium.edu.my/1350/1/Evaluation_of_anti-hypertensive_drug_utilisation_and_cost_in_Hospital_Tengku_Ampuan_Afzan%2C_Kuantan.pdf Mohd Shah, Azarisman Shah and Abdullah, Aszrin and Mohamed, Sahimi and Abdullah Ngow, Harris and Omar, Ahmad Marzuki and Ab Rahman, Jamalludin and Satwi, Sapari and Oteh, Maskon (2009) Evaluation of anti-hypertensive drug utilisation and cost in Hospital Tengku Ampuan Afzan, Kuantan. International Medical Journal Malaysia, 8 (2). pp. 29-34. ISSN 1823-4631 http://www.e-imj.com/ |
| spellingShingle | R Medicine (General) Mohd Shah, Azarisman Shah Abdullah, Aszrin Mohamed, Sahimi Abdullah Ngow, Harris Omar, Ahmad Marzuki Ab Rahman, Jamalludin Satwi, Sapari Oteh, Maskon Evaluation of anti-hypertensive drug utilisation and cost in Hospital Tengku Ampuan Afzan, Kuantan |
| title | Evaluation of anti-hypertensive drug utilisation and cost in Hospital Tengku Ampuan Afzan, Kuantan |
| title_full | Evaluation of anti-hypertensive drug utilisation and cost in Hospital Tengku Ampuan Afzan, Kuantan |
| title_fullStr | Evaluation of anti-hypertensive drug utilisation and cost in Hospital Tengku Ampuan Afzan, Kuantan |
| title_full_unstemmed | Evaluation of anti-hypertensive drug utilisation and cost in Hospital Tengku Ampuan Afzan, Kuantan |
| title_short | Evaluation of anti-hypertensive drug utilisation and cost in Hospital Tengku Ampuan Afzan, Kuantan |
| title_sort | evaluation of anti hypertensive drug utilisation and cost in hospital tengku ampuan afzan kuantan |
| topic | R Medicine (General) |
| url | http://irep.iium.edu.my/1350/1/Evaluation_of_anti-hypertensive_drug_utilisation_and_cost_in_Hospital_Tengku_Ampuan_Afzan%2C_Kuantan.pdf |
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