PROCEEDINGS : The 16th AAAP Congress SUSTAINABLE LIVESTOCK PRODUCTION IN THE PRESPECTIVE OF FOOD SECURITY, POLICY, GENETIC RESOURCES, AND CLIMATE CHANGE
Cholesterol oxidation process could happen in aorta or artery. The purpose of this research is to investigate the mechanism and getting the effective dosage of curcuminoid turmeric extract in preventing the initial process of pathogenesis atherosclerosis in vivo. There were 30 rats divided into 6...
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| Other Authors: | |
| Format: | Book Section |
| Language: | English |
| Published: |
Fakultas Kedokteran Hewan Universitas Gadjah Mada
2014
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/135271/1/proceeding%20vol.II%20Abstracts.pdf |
| _version_ | 1826049353059401728 |
|---|---|
| author | Susmiati, Trini Putro, Prabowo Purwono Pangestiningsih, Triwahyu Widayanti, Rini Airin, Claude Mona |
| author2 | Subandriyo, Subandriyo |
| author_facet | Subandriyo, Subandriyo Susmiati, Trini Putro, Prabowo Purwono Pangestiningsih, Triwahyu Widayanti, Rini Airin, Claude Mona |
| author_sort | Susmiati, Trini |
| collection | UGM |
| description | Cholesterol oxidation process could happen in aorta or artery. The purpose of this research is
to investigate the mechanism and getting the effective dosage of curcuminoid turmeric extract
in preventing the initial process of pathogenesis atherosclerosis in vivo. There were 30 rats
divided into 6 groups. Curcuminoid extract was isolated from tumeric using maseration and
methanol method, and then the extraction was tested to the rats with atherosclerosis. The
concentration of low density lipoprotein (LDL) was determinedusing cholesterol kit.
Coloring with haemathociline (HE) was used to investigate the atherosclerotic in aorta and
coronaria arteries. Curcuminoid was obtainedfrom the extraction oftumeric(1,2% from 10 kg
of tumeric). The result of LDL plasma cholesterol average count after 4-wk treatment for
each groups were: group A: 94,29-151,11 mg /di,B: 102,86- 155,55 mg /dl, C:125,71-
173,33 mg /di,D:144,28- 164,44 mg /dl,E :105,72- 155,55 mg /dl, and group F: 102,85-
138,8 mg /dl. The statistical test showed the increase of cholesterol (P<0,05),as well as LDL
cholesterol: Group A: 87,24-138,67 mg/dl,B: 94,99-140,59 mg /dl, C: 118, 24-160,57 mg /dl,
D: 118,22- 157,57 mg /dl, E :105,58-139,72 mg /dl, and F: 99,1-119,74 mg /dl (P<0,05).
Theatherosclerosisplagueswere shown by the smooth muscle cell, macrophag cell accumulation, fat cells, and fat scratches asthehistological coloring results ofaorta and
coronaria artery.It can be concluded that curcuminoid tumeric extract was still disable to prefent therosclerosis
Atherosclerosis, LDL Cholesterol, curkcuminoid tumeric extract,
aorta,coronariaartery |
| first_indexed | 2024-03-13T23:44:37Z |
| format | Book Section |
| id | oai:generic.eprints.org:135271 |
| institution | Universiti Gadjah Mada |
| language | English |
| last_indexed | 2024-03-13T23:44:37Z |
| publishDate | 2014 |
| publisher | Fakultas Kedokteran Hewan Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1352712015-11-02T08:38:54Z https://repository.ugm.ac.id/135271/ PROCEEDINGS : The 16th AAAP Congress SUSTAINABLE LIVESTOCK PRODUCTION IN THE PRESPECTIVE OF FOOD SECURITY, POLICY, GENETIC RESOURCES, AND CLIMATE CHANGE Susmiati, Trini Putro, Prabowo Purwono Pangestiningsih, Triwahyu Widayanti, Rini Airin, Claude Mona Veterinary Sciences Cholesterol oxidation process could happen in aorta or artery. The purpose of this research is to investigate the mechanism and getting the effective dosage of curcuminoid turmeric extract in preventing the initial process of pathogenesis atherosclerosis in vivo. There were 30 rats divided into 6 groups. Curcuminoid extract was isolated from tumeric using maseration and methanol method, and then the extraction was tested to the rats with atherosclerosis. The concentration of low density lipoprotein (LDL) was determinedusing cholesterol kit. Coloring with haemathociline (HE) was used to investigate the atherosclerotic in aorta and coronaria arteries. Curcuminoid was obtainedfrom the extraction oftumeric(1,2% from 10 kg of tumeric). The result of LDL plasma cholesterol average count after 4-wk treatment for each groups were: group A: 94,29-151,11 mg /di,B: 102,86- 155,55 mg /dl, C:125,71- 173,33 mg /di,D:144,28- 164,44 mg /dl,E :105,72- 155,55 mg /dl, and group F: 102,85- 138,8 mg /dl. The statistical test showed the increase of cholesterol (P<0,05),as well as LDL cholesterol: Group A: 87,24-138,67 mg/dl,B: 94,99-140,59 mg /dl, C: 118, 24-160,57 mg /dl, D: 118,22- 157,57 mg /dl, E :105,58-139,72 mg /dl, and F: 99,1-119,74 mg /dl (P<0,05). Theatherosclerosisplagueswere shown by the smooth muscle cell, macrophag cell accumulation, fat cells, and fat scratches asthehistological coloring results ofaorta and coronaria artery.It can be concluded that curcuminoid tumeric extract was still disable to prefent therosclerosis Atherosclerosis, LDL Cholesterol, curkcuminoid tumeric extract, aorta,coronariaartery Fakultas Kedokteran Hewan Universitas Gadjah Mada Subandriyo, Subandriyo Kusmartono, Kusmartono Santosa, Krishna Agung Kurnianto, Edi Purnomoadi, Agung Sodiq, Akhmad Wiryawan, Komang G 2014-11 Book Section PeerReviewed application/pdf en cc_public_domain https://repository.ugm.ac.id/135271/1/proceeding%20vol.II%20Abstracts.pdf Susmiati, Trini and Putro, Prabowo Purwono and Pangestiningsih, Triwahyu and Widayanti, Rini and Airin, Claude Mona (2014) PROCEEDINGS : The 16th AAAP Congress SUSTAINABLE LIVESTOCK PRODUCTION IN THE PRESPECTIVE OF FOOD SECURITY, POLICY, GENETIC RESOURCES, AND CLIMATE CHANGE. In: Proceedings :The 16th AAAP Congress Sustainable Livestock Production in the Perspective of Food Security, Policy, Genetic Resources, and Climate Change. Fakultas Kedokteran Hewan Universitas Gadjah Mada, Yogyakarta, pp. 2640-2643. |
| spellingShingle | Veterinary Sciences Susmiati, Trini Putro, Prabowo Purwono Pangestiningsih, Triwahyu Widayanti, Rini Airin, Claude Mona PROCEEDINGS : The 16th AAAP Congress SUSTAINABLE LIVESTOCK PRODUCTION IN THE PRESPECTIVE OF FOOD SECURITY, POLICY, GENETIC RESOURCES, AND CLIMATE CHANGE |
| title | PROCEEDINGS : The 16th AAAP Congress SUSTAINABLE LIVESTOCK PRODUCTION IN THE
PRESPECTIVE OF FOOD SECURITY, POLICY, GENETIC
RESOURCES, AND CLIMATE CHANGE |
| title_full | PROCEEDINGS : The 16th AAAP Congress SUSTAINABLE LIVESTOCK PRODUCTION IN THE
PRESPECTIVE OF FOOD SECURITY, POLICY, GENETIC
RESOURCES, AND CLIMATE CHANGE |
| title_fullStr | PROCEEDINGS : The 16th AAAP Congress SUSTAINABLE LIVESTOCK PRODUCTION IN THE
PRESPECTIVE OF FOOD SECURITY, POLICY, GENETIC
RESOURCES, AND CLIMATE CHANGE |
| title_full_unstemmed | PROCEEDINGS : The 16th AAAP Congress SUSTAINABLE LIVESTOCK PRODUCTION IN THE
PRESPECTIVE OF FOOD SECURITY, POLICY, GENETIC
RESOURCES, AND CLIMATE CHANGE |
| title_short | PROCEEDINGS : The 16th AAAP Congress SUSTAINABLE LIVESTOCK PRODUCTION IN THE
PRESPECTIVE OF FOOD SECURITY, POLICY, GENETIC
RESOURCES, AND CLIMATE CHANGE |
| title_sort | proceedings the 16th aaap congress sustainable livestock production in the prespective of food security policy genetic resources and climate change |
| topic | Veterinary Sciences |
| url | https://repository.ugm.ac.id/135271/1/proceeding%20vol.II%20Abstracts.pdf |
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