Correlation of amodiaquine sensitivity to chloroquine and quinine against Plasmodium falciparum in vitro
ABSTRACT Amodiaquine, a 4-aminoquinoline derivative has been introduced since decades ago, and yet the, use remains debatable for its side effects. Chioroquine, the least side effect of antimalarials possessing similarity in pharmacokinetic properties has been less attractive due to the development...
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| Format: | Article |
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[Yogyakarta] : Universitas Gadjah Mada
1998
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| _version_ | 1826031758946074624 |
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| author | Perpustakaan UGM, i-lib |
| author_facet | Perpustakaan UGM, i-lib |
| author_sort | Perpustakaan UGM, i-lib |
| collection | UGM |
| description | ABSTRACT
Amodiaquine, a 4-aminoquinoline derivative has been introduced since decades ago, and yet the, use remains debatable for its side effects. Chioroquine, the least side effect of antimalarials possessing similarity in pharmacokinetic properties has been less attractive due to the development of resistance worldwide. The return to amodiaquine is debatable. Comparison of the level of sensitivity of 42 isolates to amodiaquine and chloroquine using in-vitro microtesting has been carried out. Amodiaquine was shown to be more sensitive to the isolates as compared to chloroquine. The reasonably high correlation with chloroquine (r =0.62 |
| first_indexed | 2024-03-05T22:58:50Z |
| format | Article |
| id | oai:generic.eprints.org:20880 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T18:42:21Z |
| publishDate | 1998 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:208802014-06-18T00:36:43Z https://repository.ugm.ac.id/20880/ Correlation of amodiaquine sensitivity to chloroquine and quinine against Plasmodium falciparum in vitro Perpustakaan UGM, i-lib Jurnal i-lib UGM ABSTRACT Amodiaquine, a 4-aminoquinoline derivative has been introduced since decades ago, and yet the, use remains debatable for its side effects. Chioroquine, the least side effect of antimalarials possessing similarity in pharmacokinetic properties has been less attractive due to the development of resistance worldwide. The return to amodiaquine is debatable. Comparison of the level of sensitivity of 42 isolates to amodiaquine and chloroquine using in-vitro microtesting has been carried out. Amodiaquine was shown to be more sensitive to the isolates as compared to chloroquine. The reasonably high correlation with chloroquine (r =0.62 [Yogyakarta] : Universitas Gadjah Mada 1998 Article NonPeerReviewed Perpustakaan UGM, i-lib (1998) Correlation of amodiaquine sensitivity to chloroquine and quinine against Plasmodium falciparum in vitro. Jurnal i-lib UGM. http://i-lib.ugm.ac.id/jurnal/download.php?dataId=3738 |
| spellingShingle | Jurnal i-lib UGM Perpustakaan UGM, i-lib Correlation of amodiaquine sensitivity to chloroquine and quinine against Plasmodium falciparum in vitro |
| title | Correlation of amodiaquine sensitivity to chloroquine and quinine against Plasmodium falciparum in vitro |
| title_full | Correlation of amodiaquine sensitivity to chloroquine and quinine against Plasmodium falciparum in vitro |
| title_fullStr | Correlation of amodiaquine sensitivity to chloroquine and quinine against Plasmodium falciparum in vitro |
| title_full_unstemmed | Correlation of amodiaquine sensitivity to chloroquine and quinine against Plasmodium falciparum in vitro |
| title_short | Correlation of amodiaquine sensitivity to chloroquine and quinine against Plasmodium falciparum in vitro |
| title_sort | correlation of amodiaquine sensitivity to chloroquine and quinine against plasmodium falciparum in vitro |
| topic | Jurnal i-lib UGM |
| work_keys_str_mv | AT perpustakaanugmilib correlationofamodiaquinesensitivitytochloroquineandquinineagainstplasmodiumfalciparuminvitro |