| Summary: | ABSTRAK
The Efficacy of protozoal durgs that have different site of action on Eimeria tenella life cycles has been investigated.
Sixty chicken one day old were divided into 3 treated groups. While 10 chicken were used as control groups. Each animal was infected with 10,000 E.tenella's oocysts orally. The treated animals were divided into sub groups i.e. those that were drugged 2 days and those that were investigated 4 days after being infected. The drug used for treatment were sulfaquinoxaline 200 ppm, sulfaquinoxaline 62.5 ppm and diaveridine 55 ppm, and toltrazuril 75 ppm, were added in the drinking water. Seven days after being infected half of the subgroups were sacrificed, the caeca were collected and the oocysts content were counted on bases of oocysts per gram feces. The other half were coundted the same way on the 14 th day after being infected.
The results show that percentage of decrease of the oocysts due to dosge regimen of sulfaquinoxaline, sulfaquinoxaline and diaveridine or toltrazuril were 94.56%, 92.86% or 99.92% respectively. The value of treatment 4 days after being infected were 91.16%, 64.52% or 99.99%. These indicated that toltrazuril acting on both asexual and sexual stage of E. tenella has significantly the highest efficacy. There is no significant difference between treatment 2 days or 4 days after being infected. Even-though there is no significant difference between a 2-days and/or a 4-days treatment, it is recommended that for sulfaquinoxaline the 2-days treatment is more being preferrerd.
Keywords: Efficacy of protozoal durgs, oocysts
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