| Summary: | Background. Cerebral manifestation of HIV/AIDS infection is rare case. There were several variety in clinical manifestation, laboratory and neuroimaging because of immunocompromised condition. Cerebral manifestation include oportunistic infection such as toxoplasmosis, CMV encephalitis, criptoccocal meningitis, progressive multifocal leucoencephalopathy (PML), neurosphilis, primary cerebral lymphoma (PML) and primary manifestation include aseptic meningitis, meningoencephalitis and AIDS dementia complex.
Objective. To discribe clinical charactheristic patients HIV/AIDS with serebral manifestation. Method. Review of medical record patients with diagnosed HIVIA1DS from August 2003-August 2004 in Sardjito General Hospital Jogjakarta.
Result. There were 5 patients HIV/AIDS with serebral manifestation, 4 male and 1 female. Clinical manifestation include hemiparesis (80%), headache (60%), seizure (40%), decrease of conciousness level (40%) and menigeal sign (40%). Head CT Scan found serebral absces with perifocal oedem at 3 patients (60%), infarction and cerebritis in 1 patient (20%). Chest X-ray found specific process in 1 patient and milier TB in 2 patients. Laboratory examination found 3 patients with elevated IgG CMV and Toxo. Cutaneus manifestation were genital siphilis and oral candidiasis.
Conclusion. The most frequent clinical manifestation is hemiparese. Cerebral abscess is frequent in patients with HIV/AIDS seropositive. Clinical manifestations could have a wide variety and overlapping because of immunocompromissed condition
Key words : central nervous system-HIV/AIDS infection
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