| Summary: | Hipertension is one of the important risk factors that influences cardiovascular morbidity and mortality. There are many factors influencing the mechanism of hypertension, involving genetic factor, environmental factor, and the interaction between those two factors. Many conditions include excessive salt intake, sodium retention, less amount of nephrons, and endothelium-derived factors, affect hypertension mechanism. Accurate diagnosis is the early step in the management of hypertension. Many groups of antihipertensive drugs include diuretics, 13-adrenoreceptor blacker, ACE-inhibitors, Ca-antagonist, a-1 adrenoceptor blacker and antagonist of angiotensin II receptor.
Key words : hypertension - ACE-inhibitors - AIIRA - pathophysiology - management
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