Isolasi senyawa hasil oksidasi rifampisina dalam sediaan obat cair dan pengujian aktifitas mikrobiologinya
ABSTRACT The oxidation product of rifampicin in aquous preparation has been isolated and it's microbiological activity observed. The isolation was carried out by liquid-liquid extraction and preparative thin layer chromatography. The microbiological activity observed was potency determination u...
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[Yogyakarta] : Universitas Gadjah Mada
1993
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| Summary: | ABSTRACT
The oxidation product of rifampicin in aquous preparation has been isolated and it's microbiological activity observed. The isolation was carried out by liquid-liquid extraction and preparative thin layer chromatography. The microbiological activity observed was potency determination using Bacillus substilis ATCC 6633. It was produced rifampicin quinon with lower potency respect to rifampicin it self.
ABSTFtAK
Telah dilakukan isolasi senyawa hash/ oksidasi rifampisina dalam sediaan obat cair dan pengujian aktifitas mikrobiologinya. /soIasi dilakukan dengan care ekstraksi cair-cair dan krornatografi lapis tipis preperatif, sedangkan pengujian aktifitas mikrobiologi dengan care penetapan potensi menggunakan Bacillus substilis ATCC Rasq Diperoleh senyawa rifampisina kuinon dengan potensi yang lebih rendah dibandingkan dengan rifampisina awal.
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