Fractal dimension of the retinal vasculature and risk of stroke : a nested case-control study

Recent studies show associations between retinal vascular changes and small infarcts detected on brain imaging, or clinical stroke. Fractal dimension has been used as a global measure of the geometric pattern of the retinal vasculature potentially representing the complex branching pattern of the mi...

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Main Authors: Kawasaki, Ryo, Che Azemin, Mohd Zulfaezal, Kumar, Dinesh Kant, Tan, Ava Grace, Liew, Gerald, Wong, Tien Yin, Mitchell, Paul, Wang, Jie Jin
Format: Article
Language:English
English
Published: 2011
Subjects:
Online Access:http://irep.iium.edu.my/24914/4/Neurology_Vol76_Issue20.pdf
http://irep.iium.edu.my/24914/1/NEUROLOGY-2010-354571v2-Wang.pdf
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author Kawasaki, Ryo
Che Azemin, Mohd Zulfaezal
Kumar, Dinesh Kant
Tan, Ava Grace
Liew, Gerald
Wong, Tien Yin
Mitchell, Paul
Wang, Jie Jin
author_facet Kawasaki, Ryo
Che Azemin, Mohd Zulfaezal
Kumar, Dinesh Kant
Tan, Ava Grace
Liew, Gerald
Wong, Tien Yin
Mitchell, Paul
Wang, Jie Jin
author_sort Kawasaki, Ryo
collection IIUM
description Recent studies show associations between retinal vascular changes and small infarcts detected on brain imaging, or clinical stroke. Fractal dimension has been used as a global measure of the geometric pattern of the retinal vasculature potentially representing the complex branching pattern of the microvasculature, including the cerebral microvasculature. We have developed an automatic method to assess spectrum fractal dimension (SFD) of the retinal microvasculature using Fourier-transformed images. Two previous studies have reported cross-sectional associations between retinal fractal dimension and lacunar stroke. In this study, we aimed to examine the association between baseline SFD and stroke incidence using a case-control sample nested in the Blue Mountains Eye Study (BMES).
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spelling oai:generic.eprints.org:249142022-06-30T08:19:20Z http://irep.iium.edu.my/24914/ Fractal dimension of the retinal vasculature and risk of stroke : a nested case-control study Kawasaki, Ryo Che Azemin, Mohd Zulfaezal Kumar, Dinesh Kant Tan, Ava Grace Liew, Gerald Wong, Tien Yin Mitchell, Paul Wang, Jie Jin RC321 Neuroscience. Biological psychiatry. Neuropsychiatry RE Ophthalmology Recent studies show associations between retinal vascular changes and small infarcts detected on brain imaging, or clinical stroke. Fractal dimension has been used as a global measure of the geometric pattern of the retinal vasculature potentially representing the complex branching pattern of the microvasculature, including the cerebral microvasculature. We have developed an automatic method to assess spectrum fractal dimension (SFD) of the retinal microvasculature using Fourier-transformed images. Two previous studies have reported cross-sectional associations between retinal fractal dimension and lacunar stroke. In this study, we aimed to examine the association between baseline SFD and stroke incidence using a case-control sample nested in the Blue Mountains Eye Study (BMES). 2011-05-17 Article PeerReviewed application/pdf en http://irep.iium.edu.my/24914/4/Neurology_Vol76_Issue20.pdf application/pdf en http://irep.iium.edu.my/24914/1/NEUROLOGY-2010-354571v2-Wang.pdf Kawasaki, Ryo and Che Azemin, Mohd Zulfaezal and Kumar, Dinesh Kant and Tan, Ava Grace and Liew, Gerald and Wong, Tien Yin and Mitchell, Paul and Wang, Jie Jin (2011) Fractal dimension of the retinal vasculature and risk of stroke : a nested case-control study. NEUROLOGY, 76. pp. 1766-1770. ISSN 0028-3878 10.1212/WNL.0b013e31821a7d7d
spellingShingle RC321 Neuroscience. Biological psychiatry. Neuropsychiatry
RE Ophthalmology
Kawasaki, Ryo
Che Azemin, Mohd Zulfaezal
Kumar, Dinesh Kant
Tan, Ava Grace
Liew, Gerald
Wong, Tien Yin
Mitchell, Paul
Wang, Jie Jin
Fractal dimension of the retinal vasculature and risk of stroke : a nested case-control study
title Fractal dimension of the retinal vasculature and risk of stroke : a nested case-control study
title_full Fractal dimension of the retinal vasculature and risk of stroke : a nested case-control study
title_fullStr Fractal dimension of the retinal vasculature and risk of stroke : a nested case-control study
title_full_unstemmed Fractal dimension of the retinal vasculature and risk of stroke : a nested case-control study
title_short Fractal dimension of the retinal vasculature and risk of stroke : a nested case-control study
title_sort fractal dimension of the retinal vasculature and risk of stroke a nested case control study
topic RC321 Neuroscience. Biological psychiatry. Neuropsychiatry
RE Ophthalmology
url http://irep.iium.edu.my/24914/4/Neurology_Vol76_Issue20.pdf
http://irep.iium.edu.my/24914/1/NEUROLOGY-2010-354571v2-Wang.pdf
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