Antimicrobial activity of Malaysian Donax grandis extracts

The present investigation was carried out to evaluate the antibacterial activities of four different parts of Malaysian Donax grandis. Dried fruit, root, leaf and stem powder of D. grandis was successively extracted with hexane, dichloromethane and methanol using Soxhlet method. All extracts were s...

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Main Authors: Mohd Daud, Jamaluddin, Hashim, Ridzwan, Taher, Muhammad, Mohd Hassan, Husna Hawa
Format: Article
Language:English
Published: Academic Information Press 2012
Subjects:
Online Access:http://irep.iium.edu.my/26053/1/Science_Series_Data_Report_Husna_paper_publish.pdf
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author Mohd Daud, Jamaluddin
Hashim, Ridzwan
Taher, Muhammad
Mohd Hassan, Husna Hawa
author_facet Mohd Daud, Jamaluddin
Hashim, Ridzwan
Taher, Muhammad
Mohd Hassan, Husna Hawa
author_sort Mohd Daud, Jamaluddin
collection IIUM
description The present investigation was carried out to evaluate the antibacterial activities of four different parts of Malaysian Donax grandis. Dried fruit, root, leaf and stem powder of D. grandis was successively extracted with hexane, dichloromethane and methanol using Soxhlet method. All extracts were screened for its antibacterial and antifungal activity using agar disc diffusion method. The microorganisms used for antibacterial and antifungal were, Staphylococcus aureus, Bacillus cereus, Psedomonas auraginosa, Escherichia coli, Candida albicans, Candida tropicalis and Candida krusei. Streptomycin (25 μg/disc) and Nystatine (30 μg/disc) was used as standards. The extracts (40 μg/disc) showed antimicrobial activity were subjected to minimum inhibitory concentration assay by two fold dilutions method. Hexane, dichloromethane and methanol extract exhibited in-vitro antimicrobial activity. None of the hexane and dichloromethane extracts showed antifungal activity.
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spelling oai:generic.eprints.org:260532016-02-22T07:01:46Z http://irep.iium.edu.my/26053/ Antimicrobial activity of Malaysian Donax grandis extracts Mohd Daud, Jamaluddin Hashim, Ridzwan Taher, Muhammad Mohd Hassan, Husna Hawa Q Science (General) QR Microbiology The present investigation was carried out to evaluate the antibacterial activities of four different parts of Malaysian Donax grandis. Dried fruit, root, leaf and stem powder of D. grandis was successively extracted with hexane, dichloromethane and methanol using Soxhlet method. All extracts were screened for its antibacterial and antifungal activity using agar disc diffusion method. The microorganisms used for antibacterial and antifungal were, Staphylococcus aureus, Bacillus cereus, Psedomonas auraginosa, Escherichia coli, Candida albicans, Candida tropicalis and Candida krusei. Streptomycin (25 μg/disc) and Nystatine (30 μg/disc) was used as standards. The extracts (40 μg/disc) showed antimicrobial activity were subjected to minimum inhibitory concentration assay by two fold dilutions method. Hexane, dichloromethane and methanol extract exhibited in-vitro antimicrobial activity. None of the hexane and dichloromethane extracts showed antifungal activity. Academic Information Press 2012-05 Article PeerReviewed application/pdf en http://irep.iium.edu.my/26053/1/Science_Series_Data_Report_Husna_paper_publish.pdf Mohd Daud, Jamaluddin and Hashim, Ridzwan and Taher, Muhammad and Mohd Hassan, Husna Hawa (2012) Antimicrobial activity of Malaysian Donax grandis extracts. Science Series Data Report, 4 (5). pp. 30-35. ISSN 1307-119X http://www.ssdr.sciencerecord.com/auto/index.php/archive/part/4/5/3/?currentVol=4&currentissue=5
spellingShingle Q Science (General)
QR Microbiology
Mohd Daud, Jamaluddin
Hashim, Ridzwan
Taher, Muhammad
Mohd Hassan, Husna Hawa
Antimicrobial activity of Malaysian Donax grandis extracts
title Antimicrobial activity of Malaysian Donax grandis extracts
title_full Antimicrobial activity of Malaysian Donax grandis extracts
title_fullStr Antimicrobial activity of Malaysian Donax grandis extracts
title_full_unstemmed Antimicrobial activity of Malaysian Donax grandis extracts
title_short Antimicrobial activity of Malaysian Donax grandis extracts
title_sort antimicrobial activity of malaysian donax grandis extracts
topic Q Science (General)
QR Microbiology
url http://irep.iium.edu.my/26053/1/Science_Series_Data_Report_Husna_paper_publish.pdf
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