| Summary: | Dental bleaching is used to treat discolored teeth by strong oxidizing agent. The color changing of teeth might be caused by nicotine stains on cigarette smokers. Those agents may cause a harmful effect i.e. causing tongue mucosa disorder that exposed by both those carcinogenic agent dental bleaching and or cigarette smoke. The epithelial tongue might undergo changes because of cigarette smoking and carbamide peroxide exposure which eventually lead to taste disorder. The aim of this study was to investigate the influence of carbamide peroxide 10% as tooth whitener on cigarette smoke on the changes of thickness of epithelial tongue. Twenty white rats were divided into 4 groups containing of 1 control group and 3 treatment groups. Group A was no treated at all, Group B was exposed by cigarette smoke, Group C was given carbamide peroxide 10%, Group D was exposed by cigarette smoke and with carbamide peroxide 10%. Histological evaluation was done by Haematoxyline-Eosin staining and exposed by microscope and visopan to observe the thickness of epithelium tongue. The data were analyzed by one-way analysis of variance (ANOVA). The results showed the increasing epithelial layer thickness between control group and the group that was exposed by cigarette smoke. In contras, there were decreasing epithelial layer thickness between control group and treatment groups, either only given by carbamide peroxide 10% or exposed cigarette smoke and with carbamide peroxide 10%.
Key words: carbamide peroxide 10%, cigarette smoke, ephitelial layer
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