| Summary: | Madura cattle in the Sonok area are classified into Sonok, Taccek, and Conventional.
Meanwhile, the selection of cattle with high economic value is expected to support
environmentally friendly livestock production. Therefore, this study aims to identify candidate
genes associated with economic traits for Madura Cattle in the Sonok area. An in-silico study
was employed using data retrieved from published studies to obtain a list of genes that have been
studied in Madura cattle. Next, genes were clustered using Venn Diagram for grouping into
respective traits. The selected economic traits were growth, carcass, milk, and reproduction trait.
The result showed that a total of 18 genes have been studied in Madura cattle. Among these
genes, four were not associated with economic traits, while five were selected as candidate genes
because they have associations with all four specified economic traits. The selected genes are
Insulin-like Growth Factor-1 (IGF-1), Growth Hormone (GH), Growth Hormone Receptor
(GHR), Myostatin (MSTN), and Leptin (LEP). These five genes can be used as molecular
markers for economic traits. Following marker selection, a protein-to-protein interaction analysis
and association study between the selected gene to economic trait needs to be performed in
Madura Cattle within the Sonok Area.
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