A bivalent vaccine of Eimeria media and Eimeria intestinalis yields protective immunity against coccidiosis during rabbit production
Coccidiosis is the costliest disease in the rabbit industry. The kits do not obtain maternal immunity against the diseases and therefore suckling to weaning period being the riskiest time of infection. To date, control of coccidiosis is relied on the use of chemical coccidiostat as a drug or as the...
| Main Authors: | , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
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2022
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| Online Access: | https://repository.ugm.ac.id/278886/1/Hamid_KH.pdf |
| _version_ | 1826050340720476160 |
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| author | Hamid, Penny Humaidah Nugroho, Widagdo Sri Pratowo, Sigit Widayanti, Rini |
| author_facet | Hamid, Penny Humaidah Nugroho, Widagdo Sri Pratowo, Sigit Widayanti, Rini |
| author_sort | Hamid, Penny Humaidah |
| collection | UGM |
| description | Coccidiosis is the costliest disease in the rabbit industry. The kits do not obtain maternal immunity against the diseases and therefore suckling to weaning period being the riskiest time of infection. To date, control of coccidiosis is relied on the use of chemical coccidiostat as a drug or as the substance in feed. Whilst, continuous exposure to antibiotics develops resistance and contamination in the carcass. There is no commercially provided vaccine to prevent rabbit coccidiosis cases. In this report, we
processed precocious lines from the strain of Yogyakarta origin by using selection pressure to attenuate Eimeria spp. The vaccine candidate composed of 50% of each Eimeria media and Eimeria intestinalis were given orally to initiate protective immunity against rabbit coccidiosis. The
vaccinated groups with 5 x 10 2 oocyst dosage exhibited 95% less total oocyst excretion compared to the non-vaccinated group. Our experiment showed no mortality and without any significantly detrimental response of vaccinated rabbits during the observation time (P<0.0001). Since the oocysts in the vaccinated rabbits are excreted in dropped faecal samples, it provides recirculation and provokes a group immunity within the flock. A vaccine candidate is a promising tool as a more environmentally friendly strategy for sustainable rabbit production. |
| first_indexed | 2024-03-14T00:02:26Z |
| format | Conference or Workshop Item |
| id | oai:generic.eprints.org:278886 |
| institution | Universiti Gadjah Mada |
| language | English |
| last_indexed | 2024-03-14T00:02:26Z |
| publishDate | 2022 |
| record_format | dspace |
| spelling | oai:generic.eprints.org:2788862023-11-01T08:48:32Z https://repository.ugm.ac.id/278886/ A bivalent vaccine of Eimeria media and Eimeria intestinalis yields protective immunity against coccidiosis during rabbit production Hamid, Penny Humaidah Nugroho, Widagdo Sri Pratowo, Sigit Widayanti, Rini Veterinary Sciences Coccidiosis is the costliest disease in the rabbit industry. The kits do not obtain maternal immunity against the diseases and therefore suckling to weaning period being the riskiest time of infection. To date, control of coccidiosis is relied on the use of chemical coccidiostat as a drug or as the substance in feed. Whilst, continuous exposure to antibiotics develops resistance and contamination in the carcass. There is no commercially provided vaccine to prevent rabbit coccidiosis cases. In this report, we processed precocious lines from the strain of Yogyakarta origin by using selection pressure to attenuate Eimeria spp. The vaccine candidate composed of 50% of each Eimeria media and Eimeria intestinalis were given orally to initiate protective immunity against rabbit coccidiosis. The vaccinated groups with 5 x 10 2 oocyst dosage exhibited 95% less total oocyst excretion compared to the non-vaccinated group. Our experiment showed no mortality and without any significantly detrimental response of vaccinated rabbits during the observation time (P<0.0001). Since the oocysts in the vaccinated rabbits are excreted in dropped faecal samples, it provides recirculation and provokes a group immunity within the flock. A vaccine candidate is a promising tool as a more environmentally friendly strategy for sustainable rabbit production. 2022 Conference or Workshop Item PeerReviewed application/pdf en https://repository.ugm.ac.id/278886/1/Hamid_KH.pdf Hamid, Penny Humaidah and Nugroho, Widagdo Sri and Pratowo, Sigit and Widayanti, Rini (2022) A bivalent vaccine of Eimeria media and Eimeria intestinalis yields protective immunity against coccidiosis during rabbit production. In: The 2nd ICESAI 2021, 12 October 2021, Fakultas Peternakan Brawijaya Malang. https://doi.org/10.1051/e3sconf/202233500006 |
| spellingShingle | Veterinary Sciences Hamid, Penny Humaidah Nugroho, Widagdo Sri Pratowo, Sigit Widayanti, Rini A bivalent vaccine of Eimeria media and Eimeria intestinalis yields protective immunity against coccidiosis during rabbit production |
| title | A bivalent vaccine of Eimeria media and Eimeria intestinalis yields protective immunity against coccidiosis during rabbit production |
| title_full | A bivalent vaccine of Eimeria media and Eimeria intestinalis yields protective immunity against coccidiosis during rabbit production |
| title_fullStr | A bivalent vaccine of Eimeria media and Eimeria intestinalis yields protective immunity against coccidiosis during rabbit production |
| title_full_unstemmed | A bivalent vaccine of Eimeria media and Eimeria intestinalis yields protective immunity against coccidiosis during rabbit production |
| title_short | A bivalent vaccine of Eimeria media and Eimeria intestinalis yields protective immunity against coccidiosis during rabbit production |
| title_sort | bivalent vaccine of eimeria media and eimeria intestinalis yields protective immunity against coccidiosis during rabbit production |
| topic | Veterinary Sciences |
| url | https://repository.ugm.ac.id/278886/1/Hamid_KH.pdf |
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