INHIBITION OF HUMAN LOW-DENSITY LIPOPROTEINS OXIDATION BY Hibiscus radiatus CUV. CALYCES EXTRACT
ABSTRACT Hibiscus radiatus Cuv calyces extracts rich in polyphenols was screened for their potential to inhibit oxidation of human low-density lipoproteins-cholesterol (LDL-C) in vitro. The inhibition of LDL-C oxidation (antioxidant activity) was determined by measuring the formation of conjugated d...
| Main Author: | |
|---|---|
| Format: | Article |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2008
|
| Subjects: |
| _version_ | 1797019796469972992 |
|---|---|
| author | Perpustakaan UGM, i-lib |
| author_facet | Perpustakaan UGM, i-lib |
| author_sort | Perpustakaan UGM, i-lib |
| collection | UGM |
| description | ABSTRACT
Hibiscus radiatus Cuv calyces extracts rich in polyphenols was screened for their potential to inhibit oxidation of
human low-density lipoproteins-cholesterol (LDL-C) in vitro. The inhibition of LDL-C oxidation (antioxidant activity)
was determined by measuring the formation of conjugated dienes and thiobarbituric acid reagent substances
(TBARS). LDL-C oxidation was carried out in the presence of H. radiatus Cuv calyces extract (20 and 50 pM).
CUS04 (10 pM) was used as the oxidation initiator and butylated hydroxytoluene (BHT) at 50 pM was used as
standard antioxidant. The protective effect of H. radiatus Cuv. calyces extract toward human low-density
lipoproteins, complex lipid system was demonstrated by significant increase lag time (? 103 min), diminished of the
propagation rate (44 %), and diminution of conjugated dienes formation 59:42 % (50 pM) compared to control.
Keywords: antioxidant, conjugated dienes, Hibiscus radiatus Cuv, low-density lipoproteins-cholesterol |
| first_indexed | 2024-03-13T19:05:13Z |
| format | Article |
| id | oai:generic.eprints.org:27912 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T19:05:13Z |
| publishDate | 2008 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:279122014-06-18T00:24:54Z https://repository.ugm.ac.id/27912/ INHIBITION OF HUMAN LOW-DENSITY LIPOPROTEINS OXIDATION BY Hibiscus radiatus CUV. CALYCES EXTRACT Perpustakaan UGM, i-lib Jurnal i-lib UGM ABSTRACT Hibiscus radiatus Cuv calyces extracts rich in polyphenols was screened for their potential to inhibit oxidation of human low-density lipoproteins-cholesterol (LDL-C) in vitro. The inhibition of LDL-C oxidation (antioxidant activity) was determined by measuring the formation of conjugated dienes and thiobarbituric acid reagent substances (TBARS). LDL-C oxidation was carried out in the presence of H. radiatus Cuv calyces extract (20 and 50 pM). CUS04 (10 pM) was used as the oxidation initiator and butylated hydroxytoluene (BHT) at 50 pM was used as standard antioxidant. The protective effect of H. radiatus Cuv. calyces extract toward human low-density lipoproteins, complex lipid system was demonstrated by significant increase lag time (? 103 min), diminished of the propagation rate (44 %), and diminution of conjugated dienes formation 59:42 % (50 pM) compared to control. Keywords: antioxidant, conjugated dienes, Hibiscus radiatus Cuv, low-density lipoproteins-cholesterol [Yogyakarta] : Universitas Gadjah Mada 2008 Article NonPeerReviewed Perpustakaan UGM, i-lib (2008) INHIBITION OF HUMAN LOW-DENSITY LIPOPROTEINS OXIDATION BY Hibiscus radiatus CUV. CALYCES EXTRACT. Jurnal i-lib UGM. http://i-lib.ugm.ac.id/jurnal/download.php?dataId=10975 |
| spellingShingle | Jurnal i-lib UGM Perpustakaan UGM, i-lib INHIBITION OF HUMAN LOW-DENSITY LIPOPROTEINS OXIDATION BY Hibiscus radiatus CUV. CALYCES EXTRACT |
| title | INHIBITION OF HUMAN LOW-DENSITY LIPOPROTEINS OXIDATION BY Hibiscus radiatus CUV. CALYCES EXTRACT |
| title_full | INHIBITION OF HUMAN LOW-DENSITY LIPOPROTEINS OXIDATION BY Hibiscus radiatus CUV. CALYCES EXTRACT |
| title_fullStr | INHIBITION OF HUMAN LOW-DENSITY LIPOPROTEINS OXIDATION BY Hibiscus radiatus CUV. CALYCES EXTRACT |
| title_full_unstemmed | INHIBITION OF HUMAN LOW-DENSITY LIPOPROTEINS OXIDATION BY Hibiscus radiatus CUV. CALYCES EXTRACT |
| title_short | INHIBITION OF HUMAN LOW-DENSITY LIPOPROTEINS OXIDATION BY Hibiscus radiatus CUV. CALYCES EXTRACT |
| title_sort | inhibition of human low density lipoproteins oxidation by hibiscus radiatus cuv calyces extract |
| topic | Jurnal i-lib UGM |
| work_keys_str_mv | AT perpustakaanugmilib inhibitionofhumanlowdensitylipoproteinsoxidationbyhibiscusradiatuscuvcalycesextract |