THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K
ABSTRACT In our course of screening for secondary metabolite derived from marine bacterial, we isolate the antimicrobial compound co/lysmicin A from the ethyl acetate extract of Streptomyces sp Q-629K. Separation of this compound was carried out by silica gel open column chromatography. Purification...
| Main Author: | |
|---|---|
| Format: | Article |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2008
|
| Subjects: |
| _version_ | 1826033129241968640 |
|---|---|
| author | Perpustakaan UGM, i-lib |
| author_facet | Perpustakaan UGM, i-lib |
| author_sort | Perpustakaan UGM, i-lib |
| collection | UGM |
| description | ABSTRACT
In our course of screening for secondary metabolite derived from marine bacterial, we isolate the antimicrobial
compound co/lysmicin A from the ethyl acetate extract of Streptomyces sp Q-629K. Separation of this compound
was carried out by silica gel open column chromatography. Purification of an active compound was done using
HPLC C1Bwith acetonitril-water system. Determinationof chemical structure was done by 1H,13CNMR and LC-MS
analysis. Co/lysmicin A was contained in fraction 3, fraction 7.2 and fraction B.7. The antimicrobial assayed from
purified compound Fr.B.7 gave diameter inhibition approximately 13 mm against S. aureus and 12 mm against B.
subtilis .
Keywords: antimicrobial, collismycin A and marine Streptomyces sp. |
| first_indexed | 2024-03-13T19:05:17Z |
| format | Article |
| id | oai:generic.eprints.org:27939 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T19:05:17Z |
| publishDate | 2008 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:279392014-06-18T00:24:45Z https://repository.ugm.ac.id/27939/ THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K Perpustakaan UGM, i-lib Jurnal i-lib UGM ABSTRACT In our course of screening for secondary metabolite derived from marine bacterial, we isolate the antimicrobial compound co/lysmicin A from the ethyl acetate extract of Streptomyces sp Q-629K. Separation of this compound was carried out by silica gel open column chromatography. Purification of an active compound was done using HPLC C1Bwith acetonitril-water system. Determinationof chemical structure was done by 1H,13CNMR and LC-MS analysis. Co/lysmicin A was contained in fraction 3, fraction 7.2 and fraction B.7. The antimicrobial assayed from purified compound Fr.B.7 gave diameter inhibition approximately 13 mm against S. aureus and 12 mm against B. subtilis . Keywords: antimicrobial, collismycin A and marine Streptomyces sp. [Yogyakarta] : Universitas Gadjah Mada 2008 Article NonPeerReviewed Perpustakaan UGM, i-lib (2008) THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K. Jurnal i-lib UGM. http://i-lib.ugm.ac.id/jurnal/download.php?dataId=11002 |
| spellingShingle | Jurnal i-lib UGM Perpustakaan UGM, i-lib THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K |
| title | THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K |
| title_full | THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K |
| title_fullStr | THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K |
| title_full_unstemmed | THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K |
| title_short | THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K |
| title_sort | antibacterialcompoundcollismicin a derived from marine streptomyces sp q 629k |
| topic | Jurnal i-lib UGM |
| work_keys_str_mv | AT perpustakaanugmilib theantibacterialcompoundcollismicinaderivedfrommarinestreptomycesspq629k AT perpustakaanugmilib antibacterialcompoundcollismicinaderivedfrommarinestreptomycesspq629k |