Alleles of apolipoprotein E gene (APOE) as genetic determinants of dementia
Dementia is emerging as a silent epidemic for rapidly developing countries like Malaysia. Its prevalence and a generic determinant assessment were the focused objectives of this study. There were two phases in this study - an initial descriptive phase followed by an analytic phase. Data were collect...
Main Authors: | , , , , , , , |
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Format: | Proceeding Paper |
Language: | English |
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2012
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Online Access: | http://irep.iium.edu.my/27960/1/2012____8___Malaysian_Science_and_Technology_Congrss__19-21_Nov_2012.pdf |
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author | Akter, Seikh Farid Uddin Abdul Rani, Mohammed Fauzi Ab Rahman, Jamalludin Sulong, Sarina Md Aris, Mohd Aznan Phang, Ing Chia Khattak, Muhammad Muzaffar Ali Khan Bakhtiar, M. Taher |
author_facet | Akter, Seikh Farid Uddin Abdul Rani, Mohammed Fauzi Ab Rahman, Jamalludin Sulong, Sarina Md Aris, Mohd Aznan Phang, Ing Chia Khattak, Muhammad Muzaffar Ali Khan Bakhtiar, M. Taher |
author_sort | Akter, Seikh Farid Uddin |
collection | IIUM |
description | Dementia is emerging as a silent epidemic for rapidly developing countries like Malaysia. Its prevalence and a generic determinant assessment were the focused objectives of this study. There were two phases in this study - an initial descriptive phase followed by an analytic phase. Data were collected from 197 study subjects intially for the secriptive phase; 65 dementia cases and 103 age matched controls for analytic phase using a questionnaire for personal profile and other related factors. Furthermore, the standard protocols were followed to determine the frequencies of the alleles of apolipoprotein E gene (APOE). The statistical analyses were performed using the SPSS for Windows, Version 17. In addition to descriotive statistics such as percentage, pertinent inferential statistical analyses such as chi square test were performed. It appears from the inital descriptvie study that dementia was the leadinf disease (72.1%) of the identified diseases among study subjects. |
first_indexed | 2024-03-05T23:11:48Z |
format | Proceeding Paper |
id | oai:generic.eprints.org:27960 |
institution | International Islamic University Malaysia |
language | English |
last_indexed | 2024-03-05T23:11:48Z |
publishDate | 2012 |
record_format | dspace |
spelling | oai:generic.eprints.org:279602016-03-10T06:56:48Z http://irep.iium.edu.my/27960/ Alleles of apolipoprotein E gene (APOE) as genetic determinants of dementia Akter, Seikh Farid Uddin Abdul Rani, Mohammed Fauzi Ab Rahman, Jamalludin Sulong, Sarina Md Aris, Mohd Aznan Phang, Ing Chia Khattak, Muhammad Muzaffar Ali Khan Bakhtiar, M. Taher R Medicine (General) Dementia is emerging as a silent epidemic for rapidly developing countries like Malaysia. Its prevalence and a generic determinant assessment were the focused objectives of this study. There were two phases in this study - an initial descriptive phase followed by an analytic phase. Data were collected from 197 study subjects intially for the secriptive phase; 65 dementia cases and 103 age matched controls for analytic phase using a questionnaire for personal profile and other related factors. Furthermore, the standard protocols were followed to determine the frequencies of the alleles of apolipoprotein E gene (APOE). The statistical analyses were performed using the SPSS for Windows, Version 17. In addition to descriotive statistics such as percentage, pertinent inferential statistical analyses such as chi square test were performed. It appears from the inital descriptvie study that dementia was the leadinf disease (72.1%) of the identified diseases among study subjects. 2012-11 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/27960/1/2012____8___Malaysian_Science_and_Technology_Congrss__19-21_Nov_2012.pdf Akter, Seikh Farid Uddin and Abdul Rani, Mohammed Fauzi and Ab Rahman, Jamalludin and Sulong, Sarina and Md Aris, Mohd Aznan and Phang, Ing Chia and Khattak, Muhammad Muzaffar Ali Khan and Bakhtiar, M. Taher (2012) Alleles of apolipoprotein E gene (APOE) as genetic determinants of dementia. In: Malaysian Science and technology Congress (MSTC 2012), 19 - 21 Nov 2012, SIME DARBY Convention Center, Bukit Kiara, Kuala Lumpur. (Unpublished) |
spellingShingle | R Medicine (General) Akter, Seikh Farid Uddin Abdul Rani, Mohammed Fauzi Ab Rahman, Jamalludin Sulong, Sarina Md Aris, Mohd Aznan Phang, Ing Chia Khattak, Muhammad Muzaffar Ali Khan Bakhtiar, M. Taher Alleles of apolipoprotein E gene (APOE) as genetic determinants of dementia |
title | Alleles of apolipoprotein E gene (APOE) as genetic determinants of dementia |
title_full | Alleles of apolipoprotein E gene (APOE) as genetic determinants of dementia |
title_fullStr | Alleles of apolipoprotein E gene (APOE) as genetic determinants of dementia |
title_full_unstemmed | Alleles of apolipoprotein E gene (APOE) as genetic determinants of dementia |
title_short | Alleles of apolipoprotein E gene (APOE) as genetic determinants of dementia |
title_sort | alleles of apolipoprotein e gene apoe as genetic determinants of dementia |
topic | R Medicine (General) |
url | http://irep.iium.edu.my/27960/1/2012____8___Malaysian_Science_and_Technology_Congrss__19-21_Nov_2012.pdf |
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