SYNTHESIS, CHARACTERIZATIONAND ANTIMICROBIALACTIVITYOF FRIEDELIN [2, 3-d] SElENADIAZOlE
ABSTRACT The new 1, 2, 3, selenadiazole derivative (3) was prepared from friedelin (1) via the co"esponding semicarbazone (2) using Lalezari cyclization. The compounds were prepared, separated and characterized on the basis of microanalysis and spectral studies. The isolated friedelin and its s...
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| Format: | Article |
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[Yogyakarta] : Universitas Gadjah Mada
2009
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| _version_ | 1826033142514843648 |
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| author | Perpustakaan UGM, i-lib |
| author_facet | Perpustakaan UGM, i-lib |
| author_sort | Perpustakaan UGM, i-lib |
| collection | UGM |
| description | ABSTRACT
The new 1, 2, 3, selenadiazole derivative (3) was prepared from friedelin (1) via the co"esponding
semicarbazone (2) using Lalezari cyclization. The compounds were prepared, separated and characterized on the
basis of microanalysis and spectral studies. The isolated friedelin and its selenadiazole were screened in vitro for
their antimicrobial activities against various pathogenic bacterial were found to be highly active against al/ the
selected pathogens. Compound 3 showed an inhibition zone of 14 mm and 12 mm respectively against highly
resistant S. albus and C. albicans. A general mechanistic scheme for these reactions is also suggested based on
current and previous results. |
| first_indexed | 2024-03-13T19:05:30Z |
| format | Article |
| id | oai:generic.eprints.org:28007 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T19:05:30Z |
| publishDate | 2009 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:280072014-06-18T00:24:41Z https://repository.ugm.ac.id/28007/ SYNTHESIS, CHARACTERIZATIONAND ANTIMICROBIALACTIVITYOF FRIEDELIN [2, 3-d] SElENADIAZOlE Perpustakaan UGM, i-lib Jurnal i-lib UGM ABSTRACT The new 1, 2, 3, selenadiazole derivative (3) was prepared from friedelin (1) via the co"esponding semicarbazone (2) using Lalezari cyclization. The compounds were prepared, separated and characterized on the basis of microanalysis and spectral studies. The isolated friedelin and its selenadiazole were screened in vitro for their antimicrobial activities against various pathogenic bacterial were found to be highly active against al/ the selected pathogens. Compound 3 showed an inhibition zone of 14 mm and 12 mm respectively against highly resistant S. albus and C. albicans. A general mechanistic scheme for these reactions is also suggested based on current and previous results. [Yogyakarta] : Universitas Gadjah Mada 2009 Article NonPeerReviewed Perpustakaan UGM, i-lib (2009) SYNTHESIS, CHARACTERIZATIONAND ANTIMICROBIALACTIVITYOF FRIEDELIN [2, 3-d] SElENADIAZOlE. Jurnal i-lib UGM. http://i-lib.ugm.ac.id/jurnal/download.php?dataId=11070 |
| spellingShingle | Jurnal i-lib UGM Perpustakaan UGM, i-lib SYNTHESIS, CHARACTERIZATIONAND ANTIMICROBIALACTIVITYOF FRIEDELIN [2, 3-d] SElENADIAZOlE |
| title | SYNTHESIS, CHARACTERIZATIONAND ANTIMICROBIALACTIVITYOF FRIEDELIN [2, 3-d] SElENADIAZOlE |
| title_full | SYNTHESIS, CHARACTERIZATIONAND ANTIMICROBIALACTIVITYOF FRIEDELIN [2, 3-d] SElENADIAZOlE |
| title_fullStr | SYNTHESIS, CHARACTERIZATIONAND ANTIMICROBIALACTIVITYOF FRIEDELIN [2, 3-d] SElENADIAZOlE |
| title_full_unstemmed | SYNTHESIS, CHARACTERIZATIONAND ANTIMICROBIALACTIVITYOF FRIEDELIN [2, 3-d] SElENADIAZOlE |
| title_short | SYNTHESIS, CHARACTERIZATIONAND ANTIMICROBIALACTIVITYOF FRIEDELIN [2, 3-d] SElENADIAZOlE |
| title_sort | synthesis characterizationand antimicrobialactivityof friedelin 2 3 d selenadiazole |
| topic | Jurnal i-lib UGM |
| work_keys_str_mv | AT perpustakaanugmilib synthesischaracterizationandantimicrobialactivityoffriedelin23dselenadiazole |