FRAGMENTATION STUDIES OF &Delta
ABSTRACT Semisynthesisof A6.7-Anhydroerythromycin-Awas done by biomodification technique by addition of 0.2% INH into a culture fermentation of Saccharopolyspora erythraea ATCC 11635 in medium Hutchinson. The aim of this research is to studies of fragmentation pattern from new matabolite of A6.7-Anh...
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| Format: | Article |
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[Yogyakarta] : Universitas Gadjah Mada
2009
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| _version_ | 1797019823432007680 |
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| author | Perpustakaan UGM, i-lib |
| author_facet | Perpustakaan UGM, i-lib |
| author_sort | Perpustakaan UGM, i-lib |
| collection | UGM |
| description | ABSTRACT
Semisynthesisof A6.7-Anhydroerythromycin-Awas done by biomodification technique by addition of 0.2% INH
into a culture fermentation of Saccharopolyspora erythraea ATCC 11635 in medium Hutchinson. The aim of this research is to studies of fragmentation pattern from new matabolite of A6.7-Anhydroerythromycin-Aby Liquid Chromatography-MassSpectroscopy(LC-MS) and the ionization of mass spectroscopy is use by ESI (Electrospray Ionization) pattern. The FT-IR spectrometric analyzes showed a stretching vibration of C=C conjugated group at wave number 1602.7 cm-1.This C=C conjugated vibrationindicated the existence of double bond between C6and C7
(A6.7),this confirmedthat isolate containedA6.7-Anhydroerythromycin(t-hAe possibilityof A6.7was positive).For complementation, a LC-MS (Liquid Chromatography-Mass Spectroscopy) analyzes using ESI-MS (Electrospray Ionization-Mass Spectroscopy) ionization pattern was conducted to the isolate which resulted Quassimolecularions
[M+Hf of A7.8_and A6.7-AnhydroerythromycinL-CA-.MSspectrogramof the isolate,whichgave twopeaksof m/z
732.2460 and m/z 716.2522, confirmed that the m/z 732.2460possibly was A7.8-Anhydroerythromycin-A, while the m/z 716.2502andm/z 715.2522possibly were A6.7-Anhydroerythromycin-A.
Keywords: isoniazid, enoyl reduction, A6,.7-Anhidroeritromisin-Afr, agmentation,LC-MS. |
| first_indexed | 2024-03-05T23:11:56Z |
| format | Article |
| id | oai:generic.eprints.org:28044 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T19:05:37Z |
| publishDate | 2009 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:280442014-06-18T00:24:24Z https://repository.ugm.ac.id/28044/ FRAGMENTATION STUDIES OF &Delta Perpustakaan UGM, i-lib Jurnal i-lib UGM ABSTRACT Semisynthesisof A6.7-Anhydroerythromycin-Awas done by biomodification technique by addition of 0.2% INH into a culture fermentation of Saccharopolyspora erythraea ATCC 11635 in medium Hutchinson. The aim of this research is to studies of fragmentation pattern from new matabolite of A6.7-Anhydroerythromycin-Aby Liquid Chromatography-MassSpectroscopy(LC-MS) and the ionization of mass spectroscopy is use by ESI (Electrospray Ionization) pattern. The FT-IR spectrometric analyzes showed a stretching vibration of C=C conjugated group at wave number 1602.7 cm-1.This C=C conjugated vibrationindicated the existence of double bond between C6and C7 (A6.7),this confirmedthat isolate containedA6.7-Anhydroerythromycin(t-hAe possibilityof A6.7was positive).For complementation, a LC-MS (Liquid Chromatography-Mass Spectroscopy) analyzes using ESI-MS (Electrospray Ionization-Mass Spectroscopy) ionization pattern was conducted to the isolate which resulted Quassimolecularions [M+Hf of A7.8_and A6.7-AnhydroerythromycinL-CA-.MSspectrogramof the isolate,whichgave twopeaksof m/z 732.2460 and m/z 716.2522, confirmed that the m/z 732.2460possibly was A7.8-Anhydroerythromycin-A, while the m/z 716.2502andm/z 715.2522possibly were A6.7-Anhydroerythromycin-A. Keywords: isoniazid, enoyl reduction, A6,.7-Anhidroeritromisin-Afr, agmentation,LC-MS. [Yogyakarta] : Universitas Gadjah Mada 2009 Article NonPeerReviewed Perpustakaan UGM, i-lib (2009) FRAGMENTATION STUDIES OF &Delta. Jurnal i-lib UGM. http://i-lib.ugm.ac.id/jurnal/download.php?dataId=11107 |
| spellingShingle | Jurnal i-lib UGM Perpustakaan UGM, i-lib FRAGMENTATION STUDIES OF &Delta |
| title | FRAGMENTATION STUDIES OF &Delta |
| title_full | FRAGMENTATION STUDIES OF &Delta |
| title_fullStr | FRAGMENTATION STUDIES OF &Delta |
| title_full_unstemmed | FRAGMENTATION STUDIES OF &Delta |
| title_short | FRAGMENTATION STUDIES OF &Delta |
| title_sort | fragmentation studies of delta |
| topic | Jurnal i-lib UGM |
| work_keys_str_mv | AT perpustakaanugmilib fragmentationstudiesofdelta |