Effects of ferro sulphate and carbon tetrachloride in liver of rat
ABSTRACT Ferro sulphate (FeSOJ overload and carbon tetrachloride (CCI.)are chemical hepatocarcinogen. Ferro sulphate disrupts the redox balance of the cell and generates chronic oxidative stress by which modulates signaling networks related to malignant transformation. Meanwhile CCI.induces hepatic...
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[Yogyakarta] : Universitas Gadjah Mada
2010
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| Summary: | ABSTRACT
Ferro sulphate (FeSOJ overload and carbon tetrachloride (CCI.)are chemical hepatocarcinogen. Ferro sulphate disrupts the redox balance of the cell and generates chronic oxidative stress by which modulates signaling networks related to malignant transformation. Meanwhile CCI.induces hepatic damage in lipidperoxidation and decreases activities of antioxidant enzymes and generation of free radicals. The aim of this study is to investigate the effect of a pause of chemical hepatocarcinogen induced in Rattus norvegicus rats. Two months old adult male Rattus norveg |
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