Method Validation of Simvastatin in PCL-PEG-PCL Triblock Copolymer Micelles Using Uv-Vis Spectrophotometric for Solubility Enhancement Assay

Method Validation of Simvastatin in PCL-PEG-PCL Triblock Copolymer Micelles Using Uv-Vis Spectrophotometric for Solubility Enhancement Assay

Objective: This study aims to increase the solubility of simvastatin (SIM), a hydrophobic drug, by incorporating it into PCL-PEG-PCL triblock copolymer micelles and validating the assay method used, namely Uv-Vis spectrophotometric. Methods: The shake flask method was used to determine the increase...

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Bibliographic Details
Main Authors:	Patmayuni, Dewi, Saifullah Sulaiman, T.N., Zulkarnain, Abdul Karim, Shiyan, Shaum
Format:	Article
Language:	English
Published:	Innovare Academics Sciences Pvt. Ltd 2022
Subjects:	Pharmaceutical Sciences
Online Access:	https://repository.ugm.ac.id/282785/1/METHOD%20VALIDATION%20OF%20SIMVASTATIN%20IN%20PCL-PEG-PCL%20TRIBLOCK%20COPOLYMER%20MICELLES.pdf

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