Transcortical selective amygdalohippocampectomy for intractable mesial temporal lobe epilepsy: a review of outcomes in a single center
Introduction: Various surgical procedures have been found to effectively treat intractable temporal lobe epilepsy (TLE), including transcortical selective amygdalohippocampectomy (SAH), which is intended to protect the temporal lobe and to prevent interference with vascular structure. This research...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Sanglah General Hospital
2022
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| Online Access: | https://repository.ugm.ac.id/282852/1/Aris%20Catur%20Bintoro.pdf |
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| author | Bintoro, Aris Catur Arifin, Muhamad Thohar Harsono, Harsono Husni, Amin Brilliantika, Surya Pratama Bakhtiar, Yuriz Khairunnis, Novita Ikbar Askoro, Rofat Bunyamin, Jacob Hadisapurto, Soeharyo Muttaqin, Zainal |
| author_facet | Bintoro, Aris Catur Arifin, Muhamad Thohar Harsono, Harsono Husni, Amin Brilliantika, Surya Pratama Bakhtiar, Yuriz Khairunnis, Novita Ikbar Askoro, Rofat Bunyamin, Jacob Hadisapurto, Soeharyo Muttaqin, Zainal |
| author_sort | Bintoro, Aris Catur |
| collection | UGM |
| description | Introduction: Various surgical procedures have been found to effectively treat intractable temporal lobe epilepsy (TLE), including transcortical selective amygdalohippocampectomy (SAH), which is intended to protect the temporal lobe and to prevent interference with vascular structure. This research analyzed the outcome of post-operative seizure-free with transcortical selective amygdalohippocampectomy for intractable mesial temporal lobe epilepsy patients in a minimum two-year follow-up after surgery.
Methods: Data of one hundred ninety-two patients who had undergone transcortical selective amygdalohippocampectomy for non-lesional, medically intractable, temporal lobe epilepsy were analyzed.
Result: The statistical analysis indicated that Focal to Bilateral Tonic-Clonic Seizure had a more significant outcome (p=0.019) than other seizures. In all research subjects, after three, six, and twelve years of follow-up, the chance for a seizure-free after surgery was respectively 93.2 percent, 67.9 percent, and 36.7 percent with a median average survival period for all subjects of 11.00 years (95 % CI: 8.55 – 13.44)
Conclusions: Transcortical selective amygdalohippocampectomy is an effective therapy for intractable mesial temporal lobe epilepsy and provides a satisfactory outcome. The transcortical approach allows an appropriate operative field by careful dissection with limited retraction to eliminate the epileptogenic target while preventing damage to the underlying vascular and cortical structures. |
| first_indexed | 2024-03-14T00:05:57Z |
| format | Article |
| id | oai:generic.eprints.org:282852 |
| institution | Universiti Gadjah Mada |
| language | English |
| last_indexed | 2024-03-14T00:05:57Z |
| publishDate | 2022 |
| publisher | Sanglah General Hospital |
| record_format | dspace |
| spelling | oai:generic.eprints.org:2828522023-11-17T01:37:42Z https://repository.ugm.ac.id/282852/ Transcortical selective amygdalohippocampectomy for intractable mesial temporal lobe epilepsy: a review of outcomes in a single center Bintoro, Aris Catur Arifin, Muhamad Thohar Harsono, Harsono Husni, Amin Brilliantika, Surya Pratama Bakhtiar, Yuriz Khairunnis, Novita Ikbar Askoro, Rofat Bunyamin, Jacob Hadisapurto, Soeharyo Muttaqin, Zainal Central Nervous System Introduction: Various surgical procedures have been found to effectively treat intractable temporal lobe epilepsy (TLE), including transcortical selective amygdalohippocampectomy (SAH), which is intended to protect the temporal lobe and to prevent interference with vascular structure. This research analyzed the outcome of post-operative seizure-free with transcortical selective amygdalohippocampectomy for intractable mesial temporal lobe epilepsy patients in a minimum two-year follow-up after surgery. Methods: Data of one hundred ninety-two patients who had undergone transcortical selective amygdalohippocampectomy for non-lesional, medically intractable, temporal lobe epilepsy were analyzed. Result: The statistical analysis indicated that Focal to Bilateral Tonic-Clonic Seizure had a more significant outcome (p=0.019) than other seizures. In all research subjects, after three, six, and twelve years of follow-up, the chance for a seizure-free after surgery was respectively 93.2 percent, 67.9 percent, and 36.7 percent with a median average survival period for all subjects of 11.00 years (95 % CI: 8.55 – 13.44) Conclusions: Transcortical selective amygdalohippocampectomy is an effective therapy for intractable mesial temporal lobe epilepsy and provides a satisfactory outcome. The transcortical approach allows an appropriate operative field by careful dissection with limited retraction to eliminate the epileptogenic target while preventing damage to the underlying vascular and cortical structures. Sanglah General Hospital 2022-11 Article PeerReviewed application/pdf en https://repository.ugm.ac.id/282852/1/Aris%20Catur%20Bintoro.pdf Bintoro, Aris Catur and Arifin, Muhamad Thohar and Harsono, Harsono and Husni, Amin and Brilliantika, Surya Pratama and Bakhtiar, Yuriz and Khairunnis, Novita Ikbar and Askoro, Rofat and Bunyamin, Jacob and Hadisapurto, Soeharyo and Muttaqin, Zainal (2022) Transcortical selective amygdalohippocampectomy for intractable mesial temporal lobe epilepsy: a review of outcomes in a single center. Bali Medical Journal (Bali MedJ), 11 (3). pp. 1468-1475. ISSN 2302-2914 https://w.balimedicaljournal.org/index.php/bmj/article/view/3475 10.15562/bmj.v11i3.3475 |
| spellingShingle | Central Nervous System Bintoro, Aris Catur Arifin, Muhamad Thohar Harsono, Harsono Husni, Amin Brilliantika, Surya Pratama Bakhtiar, Yuriz Khairunnis, Novita Ikbar Askoro, Rofat Bunyamin, Jacob Hadisapurto, Soeharyo Muttaqin, Zainal Transcortical selective amygdalohippocampectomy for intractable mesial temporal lobe epilepsy: a review of outcomes in a single center |
| title | Transcortical selective amygdalohippocampectomy for intractable mesial temporal lobe epilepsy: a review of outcomes in a single center |
| title_full | Transcortical selective amygdalohippocampectomy for intractable mesial temporal lobe epilepsy: a review of outcomes in a single center |
| title_fullStr | Transcortical selective amygdalohippocampectomy for intractable mesial temporal lobe epilepsy: a review of outcomes in a single center |
| title_full_unstemmed | Transcortical selective amygdalohippocampectomy for intractable mesial temporal lobe epilepsy: a review of outcomes in a single center |
| title_short | Transcortical selective amygdalohippocampectomy for intractable mesial temporal lobe epilepsy: a review of outcomes in a single center |
| title_sort | transcortical selective amygdalohippocampectomy for intractable mesial temporal lobe epilepsy a review of outcomes in a single center |
| topic | Central Nervous System |
| url | https://repository.ugm.ac.id/282852/1/Aris%20Catur%20Bintoro.pdf |
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