| Summary: | Background and aims: Meals with high protein and fiber could reduce weight and improve diabetes risk factors.
Isomalto-oligosaccharide (IMO), a form of dietary fiber, could induce the afferent signal that causes appetite
suppression. However, the direct effect of fiber supplementation in the form of IMO combined with a highprotein
diet (HPF) on those parameters is still unknown. This study aims to investigate the effect of HPF on
anthropometric parameters and blood glucose regulation of healthy subjects.
Methods: Thirteen healthy subjects were given a hypocaloric high protein diet (HPD) mixed with their prepared
meals for two weeks. Followed by the HPF diet for another two weeks. Their anthropometric parameters, such as
body composition (total body weight, body fat percentage, and fat-free mass), BMI and waist circumference, and
fasting plasma glucose, were measured.
Results: Compared to pre-intervention, HPF could significantly (p ≤ 0.004) reduce the anthropometric parameters
and fasting plasma glucose. Compared to HPD, HPF could significantly (p ≤ 0.005) reduce more total body
weight, body fat percentage, and BMI. In addition, HPF could induce more satiety than HPD (higher VAS score).
Conclusion: HPF could improve the subject’s anthropometric parameters which is obviously beneficial in preventing
the risk of developing diabetes.
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