The combination of isomalto-oligosaccharides (IMO)-based dietary fiber and hypocaloric high-protein diet could improve the anthropometric profile and fasting plasma glucose of healthy adults: A repeated single-arm clinical trial
Background and aims: Meals with high protein and fiber could reduce weight and improve diabetes risk factors. Isomalto-oligosaccharide (IMO), a form of dietary fiber, could induce the afferent signal that causes appetite suppression. However, the direct effect of fiber supplementation in the form of...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English English |
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Elsevier Inc.
2022
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| Online Access: | https://repository.ugm.ac.id/283079/1/scopus.bib https://repository.ugm.ac.id/283079/2/23-The_combination_of_isomalto_dr.Dian%20tambahan.pdf |
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| author | Wijaya, Hendy Hirata, Yu Tjan, Lidya Handayani Tjahjono, Yudy Foe, Kuncoro Caroline, Caroline Setiadi, Diga Albrian Wihadmadyatami, Hevi Novita, Bernadette Dian Jong, FX Himawan Haryanto Khudrati, Wilson Christianto |
| author_facet | Wijaya, Hendy Hirata, Yu Tjan, Lidya Handayani Tjahjono, Yudy Foe, Kuncoro Caroline, Caroline Setiadi, Diga Albrian Wihadmadyatami, Hevi Novita, Bernadette Dian Jong, FX Himawan Haryanto Khudrati, Wilson Christianto |
| author_sort | Wijaya, Hendy |
| collection | UGM |
| description | Background and aims: Meals with high protein and fiber could reduce weight and improve diabetes risk factors. Isomalto-oligosaccharide (IMO), a form of dietary fiber, could induce the afferent signal that causes appetite suppression. However, the direct effect of fiber supplementation in the form of IMO combined with a high-protein diet (HPF) on those parameters is still unknown. This study aims to investigate the effect of HPF on anthropometric parameters and blood glucose regulation of healthy subjects. Methods: Thirteen healthy subjects were given a hypocaloric high protein diet (HPD) mixed with their prepared meals for two weeks. Followed by the HPF diet for another two weeks. Their anthropometric parameters, such as body composition (total body weight, body fat percentage, and fat-free mass), BMI and waist circumference, and fasting plasma glucose, were measured. Results: Compared to pre-intervention, HPF could significantly (p ≤ 0.004) reduce the anthropometric parameters and fasting plasma glucose. Compared to HPD, HPF could significantly (p ≤ 0.005) reduce more total body weight, body fat percentage, and BMI. In addition, HPF could induce more satiety than HPD (higher VAS score). Conclusion: HPF could improve the subject's anthropometric parameters which is obviously beneficial in preventing the risk of developing diabetes. © 2022 The Author(s) |
| first_indexed | 2024-03-14T00:06:22Z |
| format | Article |
| id | oai:generic.eprints.org:283079 |
| institution | Universiti Gadjah Mada |
| language | English English |
| last_indexed | 2024-03-14T00:06:22Z |
| publishDate | 2022 |
| publisher | Elsevier Inc. |
| record_format | dspace |
| spelling | oai:generic.eprints.org:2830792023-11-17T08:29:34Z https://repository.ugm.ac.id/283079/ The combination of isomalto-oligosaccharides (IMO)-based dietary fiber and hypocaloric high-protein diet could improve the anthropometric profile and fasting plasma glucose of healthy adults: A repeated single-arm clinical trial Wijaya, Hendy Hirata, Yu Tjan, Lidya Handayani Tjahjono, Yudy Foe, Kuncoro Caroline, Caroline Setiadi, Diga Albrian Wihadmadyatami, Hevi Novita, Bernadette Dian Jong, FX Himawan Haryanto Khudrati, Wilson Christianto Dietetics and Nutrigenomics Background and aims: Meals with high protein and fiber could reduce weight and improve diabetes risk factors. Isomalto-oligosaccharide (IMO), a form of dietary fiber, could induce the afferent signal that causes appetite suppression. However, the direct effect of fiber supplementation in the form of IMO combined with a high-protein diet (HPF) on those parameters is still unknown. This study aims to investigate the effect of HPF on anthropometric parameters and blood glucose regulation of healthy subjects. Methods: Thirteen healthy subjects were given a hypocaloric high protein diet (HPD) mixed with their prepared meals for two weeks. Followed by the HPF diet for another two weeks. Their anthropometric parameters, such as body composition (total body weight, body fat percentage, and fat-free mass), BMI and waist circumference, and fasting plasma glucose, were measured. Results: Compared to pre-intervention, HPF could significantly (p ≤ 0.004) reduce the anthropometric parameters and fasting plasma glucose. Compared to HPD, HPF could significantly (p ≤ 0.005) reduce more total body weight, body fat percentage, and BMI. In addition, HPF could induce more satiety than HPD (higher VAS score). Conclusion: HPF could improve the subject's anthropometric parameters which is obviously beneficial in preventing the risk of developing diabetes. © 2022 The Author(s) Elsevier Inc. 2022 Article PeerReviewed text/html en https://repository.ugm.ac.id/283079/1/scopus.bib application/pdf en https://repository.ugm.ac.id/283079/2/23-The_combination_of_isomalto_dr.Dian%20tambahan.pdf Wijaya, Hendy and Hirata, Yu and Tjan, Lidya Handayani and Tjahjono, Yudy and Foe, Kuncoro and Caroline, Caroline and Setiadi, Diga Albrian and Wihadmadyatami, Hevi and Novita, Bernadette Dian and Jong, FX Himawan Haryanto and Khudrati, Wilson Christianto (2022) The combination of isomalto-oligosaccharides (IMO)-based dietary fiber and hypocaloric high-protein diet could improve the anthropometric profile and fasting plasma glucose of healthy adults: A repeated single-arm clinical trial. Contemporary Clinical Trials Communications, 30. 10.1016/j.conctc.2022.101049 |
| spellingShingle | Dietetics and Nutrigenomics Wijaya, Hendy Hirata, Yu Tjan, Lidya Handayani Tjahjono, Yudy Foe, Kuncoro Caroline, Caroline Setiadi, Diga Albrian Wihadmadyatami, Hevi Novita, Bernadette Dian Jong, FX Himawan Haryanto Khudrati, Wilson Christianto The combination of isomalto-oligosaccharides (IMO)-based dietary fiber and hypocaloric high-protein diet could improve the anthropometric profile and fasting plasma glucose of healthy adults: A repeated single-arm clinical trial |
| title | The combination of isomalto-oligosaccharides (IMO)-based dietary fiber and hypocaloric high-protein diet could improve the anthropometric profile and fasting plasma glucose of healthy adults: A repeated single-arm clinical trial |
| title_full | The combination of isomalto-oligosaccharides (IMO)-based dietary fiber and hypocaloric high-protein diet could improve the anthropometric profile and fasting plasma glucose of healthy adults: A repeated single-arm clinical trial |
| title_fullStr | The combination of isomalto-oligosaccharides (IMO)-based dietary fiber and hypocaloric high-protein diet could improve the anthropometric profile and fasting plasma glucose of healthy adults: A repeated single-arm clinical trial |
| title_full_unstemmed | The combination of isomalto-oligosaccharides (IMO)-based dietary fiber and hypocaloric high-protein diet could improve the anthropometric profile and fasting plasma glucose of healthy adults: A repeated single-arm clinical trial |
| title_short | The combination of isomalto-oligosaccharides (IMO)-based dietary fiber and hypocaloric high-protein diet could improve the anthropometric profile and fasting plasma glucose of healthy adults: A repeated single-arm clinical trial |
| title_sort | combination of isomalto oligosaccharides imo based dietary fiber and hypocaloric high protein diet could improve the anthropometric profile and fasting plasma glucose of healthy adults a repeated single arm clinical trial |
| topic | Dietetics and Nutrigenomics |
| url | https://repository.ugm.ac.id/283079/1/scopus.bib https://repository.ugm.ac.id/283079/2/23-The_combination_of_isomalto_dr.Dian%20tambahan.pdf |
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